Pfizer begins first human tests of potential arthritis and lupus drug

NCT ID NCT07235163

Not yet recruiting Knowledge-focused Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a new drug called PF-08065010 in 100 healthy adults aged 18 to 65. The goal is to check its safety and how the body processes it, as a first step toward possibly treating rheumatoid arthritis and lupus. Participants receive either the drug or a placebo as a shot or IV, with frequent monitoring over several months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PF-08065010

What this could lead to

If successful, this could pave the way for a new treatment option for rheumatoid arthritis and lupus.

What could go wrong

This is an early Phase 1 safety study in healthy people, not patients. The drug may not work or could have side effects in later trials.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

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