Pfizer begins first human tests of potential arthritis and lupus drug

NCT ID NCT07235163

Not yet recruiting Knowledge-focused Sponsor: Pfizer Source: ClinicalTrials.gov โ†—

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tests a new drug called PF-08065010 in 100 healthy adults aged 18 to 65. The goal is to check its safety and how the body processes it, as a first step toward possibly treating rheumatoid arthritis and lupus. Participants receive either the drug or a placebo as a shot or IV, with frequent monitoring over several months.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
PF-08065010
What this could lead to
If successful, this could pave the way for a new treatment option for rheumatoid arthritis and lupus.
What could go wrong
This is an early Phase 1 safety study in healthy people, not patients. The drug may not work or could have side effects in later trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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