HEALTHY

This study tests a new vaccine called H107e/CAF®10b to prevent tuberculosis (TB). The vaccine is given to healthy adults aged 18 to 45 for the first time in humans. The main goal is to check if it is safe and how well it triggers the immune system to fight TB bacteria.

This study tests a new seasonal flu vaccine (IL-YANG quadrivalent) in healthy infants aged 6 months to under 3 years. The goal is to see if the vaccine is safe and triggers a strong immune response. Around 245 babies will receive either the new vaccine or an existing one, and res…

This early-stage study tests an experimental vaccine called V540D in 72 healthy adults. The vaccine is designed to protect against the same nine HPV types as the current GARDASIL®9 vaccine, plus additional HPV types that can cause cancer. The main goal is to check if the new vacc…

This early-stage study tests a new drug called LY3537031 in overweight, obese, and healthy volunteers. The main goal is to check safety and side effects, but researchers will also measure how much drug gets into the blood and how body weight changes. The study lasts about 49 week…

This study tests a new 'accordian' gum graft method against the standard free gingival graft for people with less than 2 mm of attached gum tissue. The goal is to see which technique better increases gum width and reduces discomfort. 36 adults with missing teeth and thin gums wil…

This study tests whether using a person's own extracted tooth as a bone graft can better preserve the socket (the hole left after tooth removal) compared to letting it heal naturally. Twenty healthy adults will be randomly assigned to either receive the tooth graft or no graft. R…

This study tests a new, non-invasive way to screen for type 2 diabetes by measuring sugar levels in fingernail keratin. Researchers compare the nail test to the standard blood test (HbA1c) in 100 adults, half with known diabetes and half without. The goal is to see if the nail te…

This study compares two types of urine tests—expressed prostatic secretion (EPS) and post massage urine (PMU)—to see which better predicts prostate cancer biopsy results. About 243 men scheduled for a prostate biopsy will provide samples. The goal is to find a less invasive way t…

This study aims to create detailed brain charts for the Chinese population by collecting MRI scans from over 10,000 healthy people of different ages. These charts will show what a normal brain looks like at each age, helping doctors detect diseases like multiple sclerosis, Alzhei…

This study tests a new ultrasound method that uses a contrast agent to create detailed images of blood vessels in the kidneys. Researchers want to see if this can help diagnose chronic kidney disease more accurately. The study includes both healthy volunteers and people with kidn…

This study tests whether teaching parents and healthcare providers about the HPV vaccine helps more girls ages 9 to 17 in Ohio Appalachia get vaccinated. About 624 parents and providers are taking part. The goal is to prevent HPV infections that can lead to cancer later in life.

This study looks at whether cranberry juice can prevent urinary tract infections (UTIs) in healthy women who are prone to them. Researchers will measure how well participants' urine blocks bacteria after drinking cranberry juice. The goal is to find out who might benefit most fro…

This study aimed to see if taking a prebiotic supplement for six weeks could lower morning stress hormone levels in healthy young adults aged 18-25 with mild to moderate stress. Participants would have provided saliva, stool, urine, and blood samples. However, the study was withd…

This study tests whether Aquamin®, a natural multi-mineral from red algae, can reduce bad breath (halitosis). Fifteen adults with self-reported halitosis will take the supplement for 90 days and report changes in their breath-related quality of life. Participants must avoid eatin…

This study tests whether vibrating the tendons, combined with robotic arm training and body awareness exercises, can improve arm and hand function in people who had a stroke at least 6 months ago. 40 participants will be assessed using standard motor function tests. The goal is t…

This study tests an experimental nasal spray called Optate in 24 adults with mild COVID-19. Researchers measure how well it lowers virus levels in the nose and improves symptoms like congestion and quality of life within 24 hours. The goal is to see if this simple treatment can h…

This study tests if menthol vapor, applied to the cheek, can trigger tear production by activating cold sensors on the eye. Thirty healthy adults will have menthol or a placebo applied near one eye, and researchers will measure if tears overflow. If it works, menthol could become…

This study tests whether taking CoQ10 supplements for 8 weeks can improve fatigue in people with Crohn's disease. About 60 adults with stable Crohn's will try one of two doses, and researchers will measure changes in fatigue and quality of life. The goal is to see if a larger, mo…

This study looked at whether taking magnesium citrate (400 mg daily for 90 days) could improve sleep quality and thinking skills in healthy Saudi adults who had poor sleep. 41 people took part, and researchers compared them to a group that didn't take any supplement. The goal was…

This study tests a short social and activity program for seniors living in care homes in Slovakia. Researchers want to see if it can improve their emotions, reduce anxiety, and decrease agitated behavior. About 200 seniors will take part, and their well-being will be measured bef…

This study looks at whether different types of exercise training can help people with Pulmonary Arterial Hypertension (PAH) feel better and have a better quality of life. Researchers are comparing whole-body aerobic training with leg-only weight training in 45 participants. The g…

This study tests whether a yeast cell wall extract (mannooligosaccharides and beta-glucans) can improve gut symptoms and gut bacteria in healthy adults aged 50-99. About 40 participants will rate their digestive symptoms daily. The goal is to see if this supplement can ease commo…

This pilot study looks at whether an 8-week nutritional supplement can reduce actinic purpura (age-related bruising) in older adults. Thirty healthy volunteers aged 55 and older will take either the supplement or vitamin C alone. Researchers will check skin changes using photos a…

This study tests whether a device that gently stimulates a nerve in the ear (called TaVNS) can reduce anxiety and distress in healthcare workers. About 90 participants will use the device and have their brain activity measured with MRI scans. The goal is to see if this simple, no…

This study looks at how much flavanols (natural compounds in foods like apples, berries, and tea) healthy adults consume. Researchers will collect urine from 200 participants aged 25-75 to measure specific breakdown products. The goal is to better understand dietary habits, not t…

This study involves 1,000 adults who use scratch-and-sniff smell cards at home to measure their sense of smell. The goal is to see if these tests can reliably detect smell loss caused by COVID-19 and track recovery over time. Participants include people with known smell loss, tho…

This study aims to find biological markers in urine and blood that can show if an athlete has been at high altitude or used the drug erythropoietin (EPO). Forty healthy runners will spend time at altitude and at sea level, and some will receive EPO injections. The goal is to impr…

This study looks at how a new prostate cancer medicine, opevesostat, behaves in the body when taken with or without another drug called itraconazole. It involves 14 healthy adult men and measures drug levels in the blood. The goal is to understand potential drug interactions, not…

This early-stage study tests the safety and how the body handles a single dose of SPY003-207 in 59 healthy adults. Participants receive either the drug or a placebo, and researchers monitor side effects and drug levels in the blood. No treatment benefit is expected; the goal is t…

This study tests the safety of a new medicine called PF-08049820, which is being developed for eczema. Healthy adults aged 18 to 65 will receive single or multiple doses of the drug or a placebo. Researchers will monitor side effects and measure how the body processes the medicin…

This study was designed to measure how compounds from a standardized ashwagandha supplement enter the bloodstream in healthy adults aged 65 and older. Participants would have taken either 120 or 240 mg of the supplement and provided blood samples over two days. The study was with…

This early-stage study is testing whether a common antibiotic (ceftriaxone) can be given as a rectal suppository instead of an injection. It involves 37 healthy Thai adults who will try both the rectal and intravenous forms to compare how well the body absorbs the medicine. The g…

This study tests a new electric bandage that creates small amounts of hydrogen peroxide to help heal wounds and prevent infections. Researchers at Mayo Clinic are putting the bandage on the healthy skin of 40 volunteers to see if it causes any discomfort, redness, swelling, or al…

This early-stage study tests whether a single shot of the experimental medicine PF-07999415 is safe in healthy adults aged 18 to 65. Participants stay at a clinic for 2 weeks and return for check-ups over several months. The study compares those who get the medicine to those who …

This study looks at how exercising in the morning versus the evening, and on an empty stomach versus after eating, changes the way your body burns energy and fat. Researchers will measure these effects in 20 healthy adults with overweight or obesity. The goal is to understand the…

This study looks at ballet dancers to find out what physical traits — like muscle strength, balance, and flexibility — might make them more likely to hurt their ankles. Researchers will compare dancers who have been injured with those who haven't, plus a group of non-dancers. The…

This study looks at whether taking melatonin can change how your heart and blood vessels respond to a cold stress test, both at rest and during exercise. Researchers will measure blood pressure, heart rate, and oxygen levels in muscles and the brain. The study involves 100 health…

This study looks at how the sugars, fats, and proteins in breast milk differ between mothers and change over time. It also explores how these differences affect the growth of healthy bacteria in a baby's gut. About 395 pregnant women who plan to breastfeed for at least 6 months a…

This study aims to improve brain scanning technology to better measure chemicals in the brain. Researchers will test new methods on 30 healthy adults using high-field MRI machines. The goal is to make scans faster and more accurate, but this study does not test any treatment or t…

This study looks at two different ways to train the brain using real-time MRI feedback. Sixty healthy adults will learn to control a key emotion-related brain region. The goal is to see which method works better and how it affects empathy.

This study looks at how a drug called enlicitide is processed in the body when given as different tablet types. Researchers will measure drug levels in the blood and check for side effects. 30 healthy adults will participate to help understand the best way to take this medication…

This study looks at how different types of cannabis oil (high or low CBD-to-THC ratio) affect stress and impulse control in healthy adults aged 19-35 who use cannabis occasionally. Twenty participants will undergo brain scans and stress tests after taking cannabis oil or a placeb…

This study looks at whether giving a probiotic (Bifidobacterium longum subsp. infantis) to healthy, breastfed infants for 21 days increases the amount of good bacteria in their stool. The study includes 120 infants born by C-section or vaginal delivery, all under 7 days old. Rese…

This study checks if survodutide enters the body the same way when given by a pre-filled syringe or a pre-filled pen. About 56 healthy or overweight adults aged 18–55 will receive a single dose of each method in random order. The goal is to see if the two delivery methods are equ…

This study enrolls 66 healthy adults to provide comparison data for the Mayo Clinic Adult Congenital Heart Disease Registry. Participants must have no heart conditions, normal blood pressure, and a BMI of 30 or less. Researchers will measure oxygen use and heart function to bette…

This study looks at why insulin doesn't widen blood vessels as it should in people with obesity and insulin resistance. Researchers test if blocking certain nerve signals can help insulin work better to improve blood flow and glucose uptake. About 36 adults aged 18-60 with obesit…

This study looks at whether certain brain wave patterns (called gamma oscillations) can predict how well ketamine therapy works for people with treatment-resistant depression. Researchers will measure brain activity using EEG before and during ketamine treatment, and track depres…

This study aimed to see if a device called LabClasp could accurately estimate blood lactate levels without needing a needle. It planned to test healthy adults during exercise and ICU patients. However, the study was withdrawn before enrolling anyone, so no results are available.

This study looks at how a common asthma medicine (fluticasone propionate) changes gene activity and cell types in the airways of 30 healthy adults. Participants will use an inhaler for 4 weeks and have a bronchoscopy (a camera test of the lungs) before and after. The goal is to u…

This study looks at whether HIV infection disrupts the body's internal clock, which could lead to health problems like diabetes and heart disease. Researchers will track gene activity at different times of day in 80 people with and without HIV. The goal is to understand how HIV a…

This study looks at whether a digital platform called mindline.sg can help healthy adults in Singapore improve their mental health knowledge, emotional wellbeing, quality of life, and work performance. About 300 participants with mild to moderate mental health symptoms will eithe…

This study aims to develop better lab tests to diagnose and monitor two rare kidney diseases called aHUS and C3G. Researchers will analyze blood, cells, and kidney tissue from 180 patients and healthy volunteers. The goal is to find specific markers that help doctors choose the r…

This study looks at how a personalized, calorie-restricted diet affects metabolism in overweight or obese Chinese adults. About 112 people took part, including some with normal weight for comparison. Over 12 weeks, researchers measured how the body burns energy and processes food…

This study looks at how amino acids change the way the body releases glucagon and insulin compared to sugar alone. Researchers will test 30 people who are healthy, have type 2 diabetes, or are obese. The goal is to better understand these hormone controls, not to provide a treatm…

This study was designed to test the safety of a new drug, LEO 142397, in healthy volunteers. It was planned to give either a single dose or daily doses for 14 days to see how the body handles the drug and what effects it has. However, the study was withdrawn before any participan…

This study looks at how a low dose of ketamine changes brain activity in 35 healthy adults. Participants get two brain scans and have their symptoms rated. The goal is to understand brain processes linked to psychosis, not to treat any disease.

This study was designed to see if adults aged 65 and older could understand the science behind pain and change how they think about it. Researchers planned to teach pain neuroscience and measure changes in knowledge and attitudes. However, the study was withdrawn before any parti…

This study aimed to see if touching a virtual hand with your real hand makes it feel more like your own. Researchers planned to test this in 30 healthy, right-handed adults using VR headsets and movement tasks. The study was withdrawn before any participants enrolled, so no resul…

This study tests a research PET scanner that can take pictures of most of the body at once, unlike current machines that only scan small sections. About 268 healthy adults and people with cognitive issues will be scanned to see how well the machine works. The goal is to learn how…

This study looks at how two different versions of the drug aramchol are absorbed by the body. Sixteen healthy adults aged 18 to 45 will take both forms at different times, and researchers will measure drug levels in their blood. The goal is to see if the new granule form works si…

This study looks at 170 people whose major depression is in remission to see if brain activity changes after mild magnetic stimulation can predict if depression will return. Researchers use a special cap that shines light on the brain to measure blood flow while applying targeted…

This study tests a new drug called LY3537031 in 46 healthy adults. Researchers want to see how much of the drug gets into the blood and how fast the body removes it when injected under the skin in different spots or into a vein. The goal is to learn about the drug's behavior and …

This study aims to see if the way a person's small intestine absorbs sugar can predict how much weight they lose after bariatric surgery. Researchers will compare obese patients scheduled for surgery with lean individuals. They will measure sugar absorption and gene changes in th…

This study was designed to see if two different exercise techniques—postural reconstruction and muscle stretching—change brain activity during a simple ankle movement. It planned to use brain scans (SPECT) in healthy adults aged 18 to 35. However, the study was withdrawn before a…

This early-stage study tests a new drug, LY4005130, in 118 healthy adults to see if it is safe and how the body processes it. Participants receive either a single dose or multiple doses under the skin or into a vein. The study monitors side effects and measures drug levels in the…

This study uses a special PET/MRI scan to track white blood cells in the brain. Researchers want to see if these cells enter the brain in people with fibromyalgia, chronic fatigue syndrome, or multiple sclerosis. The goal is to better understand brain inflammation and improve fut…

This study tests a new formulation of survodutide, a medicine being developed for obesity and liver conditions. About 100 healthy adults aged 18-65 with a BMI of 27-40 will receive weekly injections of either the current or new formulation for 28 weeks. Researchers will compare h…

This study looks at whether manual therapy (like massage or joint mobilization) can improve physical performance in healthy, active adults. Sixty participants will do sports tests before and after a manual therapy session to see if it changes strength, flexibility, or speed. The …

This study in 24 healthy adults compares how much metronidazole enters the bloodstream when applied as a gel or cream to skin pretreated with a micropatch. The goal is to see which formulation delivers the drug better. Participants will have blood samples and skin color measureme…

This early-stage study tests a new drug called LY3981314 in healthy volunteers to see if it is safe and how the body handles it. About 76 participants will receive a single injection under the skin and be monitored for up to 25 weeks. The study does not aim to treat any disease.

This study looks at why cranberry juice helps some women avoid urinary tract infections (UTIs) but not others. Researchers think the answer may lie in the gut microbiome—the collection of bacteria in the digestive system. Over 3 weeks, 160 healthy women who are prone to UTIs will…

This study looks at how well the body absorbs omega-3 fatty acids (EPA and DHA) from two different algae sources compared to fish oil and a placebo. 120 healthy adults took one of the supplements daily for 6 weeks. Researchers measured omega-3 levels in the blood to see which sou…

This study looks at whether teaching adults cooking and food skills can lower stress, reduce food waste, and improve their diet. About 180 adults aged 18 and older who can attend in-person classes will take part. Researchers will measure food waste before and after the classes to…

This pilot study uses special PET scans to see where opioid receptors are located in the brain and body, and how they bind to different substances. Researchers will study up to 60 adults, including some with opioid use disorder and some healthy volunteers. The goal is to better u…

This study looks at how grapefruit juice changes the way the blood thinner edoxaban works in the body. Fourteen healthy adults aged 19 to 50 will take edoxaban with and without grapefruit juice to see if it affects drug levels and blood clotting. The goal is to understand possibl…

This study looks at how different health issues—like stroke, vision problems, inner ear disorders, and spine conditions—affect a person's balance. Researchers will test 330 people using simple physical exams and devices to see if they can better tell what is causing the balance t…

This study is an early-stage trial to check if a single dose of ALXN2030 is safe and tolerable in healthy adults. About 48 participants will receive either the drug or a placebo. Researchers will monitor side effects and measure how the drug behaves in the body. This trial does n…

This study looks at how the brain changes old movement memories, like a bad golf swing or piano technique. Researchers will use EEG to measure brain activity and apply gentle electrical stimulation to see if it helps people learn a new movement. The study involves 30 healthy adul…

This study looks at how certain fats in the blood change over 24 hours in people with night eating syndrome compared to healthy volunteers. Researchers want to see if unusual eating patterns disrupt these natural rhythms. The study involves 12 participants and includes measuring …

This study invites anyone over 18 to join an online registry to help researchers learn more about brain health and diseases like Alzheimer's. Participants fill out questionnaires and take online thinking tests from home. The goal is to speed up research and find ways to keep brai…

This study looks at how a ketone drink changes the way muscles take up sugar after a meal. Researchers will measure sugar levels in the forearm of 14 healthy adults aged 18-40. The goal is to learn more about how ketones help regulate blood sugar, which could inform future treatm…

This study looks at whether being obese during pregnancy can affect a baby's brain development. Researchers will use MRI scans on newborns at 2 weeks old to check for differences. The study involves 13 healthy mothers with either a normal weight or obesity. It aims to gather info…

This early-stage study looks at how a single dose of an experimental medicine (PF-08653944) is absorbed when injected into the abdomen, thigh, or upper arm. It involves 54 overweight or obese adults and aims to check safety and how the drug moves through the body. Participants wi…

This study looks at how the cerebellum, a part of the brain, helps us learn and adjust speech. Researchers will study people with cerebellar ataxia (a condition affecting coordination) and healthy volunteers. They will use speaking tasks, brain scans (MRI), and a technique that t…

This study looks at how a single session of short, controlled low-oxygen breathing (acute intermittent hypoxia) affects hand strength in healthy adults aged 18-70. Researchers want to understand how this technique changes spinal cord activity and nerve connections. The goal is to…

This study looks at whether a special UV flashlight, often used to spot pet urine, can change nitric oxide levels on human skin. Researchers will measure gas released from the ear, hand, or forehead during light exposure. The goal is to develop a simpler way to measure nitric oxi…

This study tests whether Nezavist is safe for healthy adults and what dose the body can handle. Thirty-two volunteers will receive either the drug or a placebo. The results will guide future research on using Nezavist to reduce alcohol consumption in people with alcohol use disor…

This study looks at how blood moves through the gut after eating in people with postprandial hypotension (a drop in blood pressure after meals). Researchers will use MRI scans and a hormone-blocking drug to understand the role of a hormone called GIP. The goal is to learn more ab…

This early-stage study tests a single dose of the experimental drug remternetug in 24 healthy Chinese adults. Researchers will check for side effects and measure how the drug moves through the body. The study lasts up to 25 weeks and does not aim to treat any disease.

This study looks at how the kidney processes glycolate into oxalate in 15 healthy adults. Participants follow a low-oxalate diet and receive a special tracer to track the conversion. The goal is to better understand oxalate production, which can lead to kidney stones.

This study looks at how many follow-up visits are needed for people who wear contact lenses. Researchers want to find the best schedule for both new and experienced wearers to keep eyes healthy and patients happy. About 300 healthy adults aged 18 to 40 will take part.

This study looks at how a common heart medication, diltiazem, changes the amount of the cancer drug nemtabrutinib in the blood. About 26 healthy adults will take nemtabrutinib with and without diltiazem to see how the combination affects drug levels and safety. The goal is to gat…

This study looks at how being overweight during pregnancy might affect a baby's brain growth. Researchers will compare brain scans and development tests of babies born to mothers with normal weight versus those with obesity. The goal is to understand if inflammation from obesity …

This study aims to improve how MRI scans work by testing new software and hardware in healthy adults aged 18 and older. Researchers will compare standard MRI images with new research images to see if the new methods provide clearer or more useful information. Participants will un…

This study explores whether pain can be detected by measuring the skin's electrical activity. Thirty-seven healthy volunteers will undergo a cold water pain test while their skin signals are recorded. The goal is to develop an algorithm that identifies pain levels, which could le…

This study looks at whether giving parents recipes and advice on adding fresh meat and vegetables to their toddler's diet can improve key nutrients like iron and zinc. About 80 healthy children aged 24-42 months will either get this extra help or follow standard healthy eating gu…

This study aims to improve how we measure fats and energy use in blood samples. Healthy adults will provide blood from a vein and from finger sticks, including one done at home with a mail-in kit. Researchers will compare these methods to find the best way to analyze fatty acids …

This study looks at how visible light and UVA1 affect skin redness and tanning in people with different skin types. Researchers will test 14 healthy volunteers to better understand these reactions and improve how light testing is done. The goal is to gather knowledge, not to trea…

This study looks at whether compounds in olive oil called polyphenols can improve heart health by changing cholesterol levels, reducing inflammation, and affecting gene activity. Researchers will test two types of olive oil in 44 healthy, overweight, or obese adults aged 20-45. T…

This study looks at how children aged 1-3 absorb iron from special nutrient supplements. Researchers will compare healthy children and those with mild undernutrition in rural Kenya. The goal is to learn more about iron absorption to help design better supplements in the future. P…

This study looks at how natural compounds in strawberries and raspberries (called polyphenols) affect gut bacteria and inflammation in overweight adults. About 105 participants will eat berries, fiber, or a combination for 4 weeks. Researchers will measure blood and stool markers…

This early-stage study tests a single injection of a long-acting form of letrozole in 90 healthy post-menopausal women. The goal is to see how the body processes the drug and whether it is safe. No treatment is being given for any disease.

This study looks at whether daily breathing exercises can improve mental and physical well-being in healthy adults. 150 participants will be split into three groups: one doing stronger breathing exercises, one doing very light exercises, and one just tracking health data. The goa…

This study looks at whether a fermented papaya supplement can improve driving performance in healthy adults aged 70 to 80. Participants take three doses of the supplement and then complete a driving simulator test to see if they make fewer errors. The goal is to understand if the…

This study examines tear proteins in 20 children who used orthokeratology (ortho-k) lenses for at least 6 months. Researchers want to find out why some kids have better myopia control than others. By comparing protein levels between good and poor responders, they hope to improve …

This study looks at how ketamine affects brain signals in 120 healthy adults. Participants receive either a study drug or placebo for 4 days and undergo brain scans before and after. The goal is to better understand brain changes linked to psychosis, not to treat any disease.

This early-stage study tests the safety and how the body processes three different forms of an experimental drug called idazoxan in 150 healthy adults. Participants take a single dose and are monitored for side effects and drug levels in the blood. The goal is to gather safety da…

This study looks at whether giving extra parenting support to families with very young children in Flint, Michigan can help kids' development and mental health after the water crisis. About 486 families with babies up to 3 months old took part. Researchers measured parenting stre…

This study aims to find better ways to collect and analyze breath samples from 1,000 people, including those with and without lung disease. The goal is to improve methods for future research, not to test a treatment. Participants will simply provide breath samples for analysis.

This study tests a new, pill-sized camera on a string (OFDI capsule) that people swallow while awake to take detailed pictures of the upper small intestine. Researchers want to see if it's comfortable and works well in 108 volunteers, including healthy adults and people with celi…

This study looks at how exercise changes fat (adipose) tissue and how those changes might improve health as we age or if we have obesity. Researchers will measure immune cells and inflammatory markers in fat tissue samples from 56 healthy adults before and after exercise. The goa…

This study looks at how breastfeeding influences the immune system and gut bacteria in Filipino infants. Researchers will track 60 healthy babies from birth to 12 months, with an optional 2-year follow-up. They will test blood and stool samples to understand immune markers and gu…

This study looks at whether a non-invasive device that temporarily changes brain activity (called rTMS) can affect how healthy adults make decisions. It involves two 2-3 hour visits and uses questionnaires to measure impulsiveness. The study is not a treatment—it aims to gather k…

This study looks at whether taking creatine for a week helps trained breath-hold divers cycle longer and harder while holding their breath. Twenty-six healthy divers will either get creatine or a placebo, then do a breath-hold cycling test. The goal is to see if creatine improves…

This study looks at whether a 12-week after-school sports program can help girls ages 8-10 in rural California become more physically active. About 30 girls will take part in the program, which introduces different sports and builds physical skills. Researchers will check if the …

This study looks at 100 healthy 8-year-olds to see if being fed breast milk, milk-based formula, or soy-based formula during their first year affects their language skills and brain function. Researchers use brain scans and language tests to compare the three groups. The goal is …

This study looks at how the body processes a drug called LY4064809. Eight healthy adults will receive the drug by mouth and by IV to see what percentage enters the bloodstream. Participants stay at the research center for 14 days, and the study lasts about 21 days. There is no tr…

This study looks at how what a child eats in the morning influences their thinking and brain function. Researchers will test 151 children aged 9-10, including those with obesity, using psychological assessments and brain scans. The goal is to understand the link between morning n…

This study looks at how aspirin works when given as a shot compared to a pill in 40 healthy adults aged 18 to 55. Researchers will measure safety, drug levels in the blood, and effects on blood clotting. The goal is to understand the differences between the two forms of aspirin.

This study aimed to see if insulin given as a nasal spray reaches the brain and spinal fluid in healthy adults aged 36 to 55. Participants would have received one dose of low-dose insulin, high-dose insulin, or a placebo, then provided fluid samples over 40 minutes. The study was…

This study was designed to test how easy and safe a new watch-like device (Watch-TEA) is to use. It was planned for healthy adults to wear the device for a few days and report any skin irritation or discomfort. The goal was to gather information that could help develop the device…

This observational study looks at why about 43% of people with multiple sclerosis (MS) feel their walking gets worse the longer they walk. Researchers will measure changes in walking patterns and brain activity in 70 MS patients and 30 healthy volunteers during short and long wal…

This early-stage study is testing a new drug called LH-001 in 56 healthy adults aged 18 to 60. The main goal is to see if the drug is safe and what side effects it might cause. Researchers will also measure how the drug moves through the body. This study is currently on hold.

This study looks at how fish oil and red wine change certain markers in the blood and urine that are linked to inflammation and cell stress. It involves 40 healthy adults who take different combinations of fish oil, red wine, or alcohol. The goal is to better understand how these…

This study was designed to test whether tartrazine, a common food dye, could temporarily make skin transparent in healthy volunteers. Researchers planned to apply different doses to the skin and take pictures to see if it improved visibility of structures beneath the skin. The st…

This study looks at how insulin in the brain changes blood flow and nerve activity in healthy adults aged 18-45. Researchers will measure blood flow in the brain and legs, and nerve signals to muscles. No treatment is given—this is an observation-only study to better understand h…

This early-stage study is testing two different versions of MK-1167, an experimental medicine being developed for Alzheimer's disease, in 16 healthy adults. The main goal is to see how the drug moves through the body and to check its safety before testing it in people with Alzhei…

This study looks at how air pollution and the body's internal clock (circadian rhythm) interact in people with asthma. Researchers will measure tiny molecules called microRNAs in sputum samples from 20 adults with and without asthma, collected at different times over 48 hours. Th…

This early-phase study is testing a new radioactive tracer called [18F]FTP in 29 healthy adults. The goal is to see how the tracer moves through the body and brain using PET/CT scans, and to check its safety. This research helps develop better tools for brain imaging, but does no…

This study looks at how anti-inflammatory drugs change fats in the blood. Healthy adults donate blood, which is then treated with drugs in a lab. Researchers measure many different fats to find new effects or side effects of these drugs. The goal is to better understand how these…

This study looks at how your body's daily rhythms (chronobiome) change with age and sex. Researchers will analyze blood samples from 48 healthy adults—young (18-30) and older (55-75)—to find differences in proteins. No treatment is given; the goal is simply to learn more about ho…

This study uses a special MRI technique to measure brain stiffness in people with Alzheimer's, mild cognitive impairment, and healthy volunteers. Researchers want to see if brain stiffness can serve as a new marker to detect Alzheimer's disease. The study involves 450 participant…

This study collects lymph fluid from the chest of 24 people (some with MS, some healthy) to compare immune cells in the blood versus deep in the lymphatic system. In MS participants, researchers will also look at how these cells change after treatment with the approved drug ofatu…

This study looks at how working night shifts changes the bacteria in your gut, which might increase the risk of certain diseases. Researchers will compare the gut bacteria of 12 healthy male night shift workers and day workers over time. The goal is to understand how sleep and wo…