Reading the Body's stress signal from the skin

NCT ID NCT03243448

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This study is testing a new, non-invasive way to measure the body's sympathetic nervous system — the part that controls the 'fight-or-flight' response. Researchers will record nerve activity from the skin of about 1,000 people, including healthy volunteers and those with conditions like high blood pressure, heart failure, or sleep apnea. The goal is to see if this simple skin recording can reliably estimate sympathetic tone, which could make it easier for doctors to monitor and understand these conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
non-invasive skin sympathetic nerve activity recording
What this could lead to
If successful, this could provide a simple, non-invasive way to monitor the body's stress response, potentially helping doctors understand and manage conditions linked to sympathetic overactivity.
What could go wrong
This is an early-stage method validation study, not a treatment trial. The technique may not prove reliable or practical in everyday clinical settings, and it does not test any therapy.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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