Urine test showdown: could a simple sample replace needle biopsy for prostate cancer?

NCT ID NCT01441687

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of urine samples—expressed prostatic secretion (EPS) and post-massage urine (PMU)—to see which one better predicts whether a prostate biopsy will find cancer. About 243 men scheduled for a prostate biopsy will provide both samples, and researchers will check which test matches the biopsy results more accurately. The goal is to find a less invasive way to help decide who really needs a biopsy.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chinn & Chinn Urology Associates, Inc.

    Arcadia, California, 91006, United States

  • Citrus Valley Urologic Medical Group

    Glendora, California, 91741, United States

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • City of Hope- South Pasadena Cancer Center

    South Pasadena, California, 91030, United States

  • Dr. Felix Chi-Ming Yip

    Monterey Park, California, 91754, United States