Scientists peer inside the body to map opioid receptors

NCT ID NCT05528848

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study will use special PET scans to measure opioid receptor binding in the brain, spinal cord, and other organs in up to 60 adults, including healthy volunteers and people with opioid use disorder. The goal is to better understand how opioids affect the whole body, not just the brain. Participants may receive a medication that blocks opioid receptors to see how binding changes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Pennsylvania, Perelman School of Medicine

    Philadelphia, Pennsylvania, 19104, United States

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