No-Radiation bone scan could spot fracture risk early

NCT ID NCT06567054

Ongoing Diagnosis Sponsor: POROUS GmbH Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new ultrasound device that measures bone properties in the lower leg to predict fracture risk in adults over 55. It aims to see if it works as well as or better than standard DXA scans, without using radiation. Researchers will follow 1,600 participants for three years, tracking new fractures and comparing results from both devices.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: POROUS R3C ultrasound device
What this could lead to: If successful, this device could offer a safer, radiation-free way to predict fracture risk and catch bone weakness earlier than current methods.
What could go wrong: This is an early-stage study with no direct treatment benefit. The device's accuracy compared to DXA is still unproven, and results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Bone Diseases, Metabolic bone fracture hip fracture osteoporosis Osteoporotic Fractures spinal fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY OSTEOPENIA OSTEOPOROSIS

Contacts and locations

Locations

Centre of Muscle and Bone Research (ZMK), Charité Universitätsmedizin Berlin, Campus Benjamin Franklin

Berlin, State of Berlin, 12207, Germany
Department for Orthopedy, Trauma and Reconstructive Surgery, Section of Geriatric Traumatology, University Hospital Halle (Saale)

Halle, 06120, Germany
Department of Endocrinology, Reproductive Medicine and Osteology Clinic for Gynecology and Obstetrics, University Hospital of Giessen and Marburg

Marburg, 35043, Germany
Department of Rheumatology, Charité Universitätsmedizin Berlin, Charite Campus Mitte

Berlin, State of Berlin, 10117, Germany
Division for Endocrinology and Metabolism, Department of Medicine 3, Medical University Vienna

Vienna, 1090, Austria
VieCuri Medisch Centrum, Department of Internal Medicine, Venlo

Venlo, 5912 BI, Netherlands

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