Pfizer tests where to inject new Weight-Loss drug for best effect

NCT ID NCT07400679

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This early-stage study tests a single dose of the experimental drug PF-08653944 in 54 overweight or obese adults. Researchers want to see how the drug is absorbed when injected into the abdomen, thigh, or upper arm. The study also monitors safety through blood tests and vital signs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
PF-08653944 (also called MET097)
What this could lead to
If successful, this study could help determine the best injection site for future trials of this medicine for weight management.
What could go wrong
This is an early Phase 1 study with only 54 participants, so results may not apply to larger populations. The medicine may cause side effects like changes in blood tests.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • New Haven Clinical Research Unit

    New Haven, Connecticut, 06511, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.