Can salt intake explain racial differences in bone and blood pressure health?

NCT ID NCT05537857

First seen Jul 31, 2026 ยท Last updated Jul 31, 2026

Summary

This study investigates whether people of different racial and ethnic backgrounds process calcium and sodium differently when eating high versus low amounts of salt. Healthy adults who are Black, White, Hispanic, or Asian will follow controlled diets with either typical Western salt levels or lower recommended levels, and researchers will measure how much calcium their bodies absorb and how much calcium and sodium they excrete. The goal is to understand if current dietary advice, which often promotes milk, may need to be personalized to better protect against conditions like osteoporosis and high blood pressure.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Controlled diets with high and low salt content, using lactose-free milk as a calcium source
What this could lead to
If successful, this could help tailor dietary salt and calcium recommendations to different racial and ethnic groups, potentially reducing risks of osteoporosis and hypertension.
What could go wrong
This is an early-stage, small study (66 participants) that measures short-term metabolic responses, not long-term health outcomes. Results may not apply to everyone or predict real-world disease risk.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • San Diego State University

    San Diego, California, 92182, United States

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