Tiny patches could boost skin drug delivery
NCT ID NCT05929794
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study in 24 healthy adults tests whether using a micropatch before applying metronidazole gel or cream improves how much drug gets into the bloodstream. Participants receive both formulations at different times, and researchers measure drug levels and skin changes. The goal is to see if micropatches can enhance topical drug delivery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Metronidazole 0.75% topical gel and cream
- What this could lead to
- If successful, this could show that micropatches improve how well topical drugs absorb through skin, potentially leading to more effective treatments for skin infections.
- What could go wrong
- This is a small, early-phase study in healthy people, not patients. It only measures drug levels in blood, not actual treatment effectiveness. Results may not apply to diseased skin.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Iowa
Iowa City, Iowa, 52242, United States
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