Tiny patches could boost skin drug delivery

NCT ID NCT05929794

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study in 24 healthy adults tests whether using a micropatch before applying metronidazole gel or cream improves how much drug gets into the bloodstream. Participants receive both formulations at different times, and researchers measure drug levels and skin changes. The goal is to see if micropatches can enhance topical drug delivery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Metronidazole 0.75% topical gel and cream

What this could lead to

If successful, this could show that micropatches improve how well topical drugs absorb through skin, potentially leading to more effective treatments for skin infections.

What could go wrong

This is a small, early-phase study in healthy people, not patients. It only measures drug levels in blood, not actual treatment effectiveness. Results may not apply to diseased skin.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Iowa

    Iowa City, Iowa, 52242, United States