University Of Iowa

This study is testing whether psilocybin (from magic mushrooms) or ketamine (an anesthetic) works better when combined with therapy to help people reduce heavy drinking. Researchers will compare these two psychedelic treatments in 80 adults with moderate to severe alcohol use dis…

This study is testing whether a 6-week brain training program can help middle-aged adults stick to a regular exercise routine. Researchers want to see if improving mental focus and self-control makes it easier to adopt healthy habits, which may help reduce the risk of developing …

This study is testing a custom-made carbon fiber foot brace to see if it can reduce the pressure and force on the feet of people with lower leg injuries. Researchers will measure how walking changes with the brace and see if special training with visual feedback helps people use …

This study is testing how different heel heights in a special carbon fiber leg brace affect pressure on the foot and pain levels during walking. Researchers will measure forces and motion as 20 adults with painful lower leg injuries walk with and without the brace. The goal is to…

This study aims to test if special sensors can reliably measure the forces inside carbon fiber ankle-foot braces (AFOs). Researchers will recruit 60 participants, including healthy adults and people who regularly use AFOs with or without nerve damage. The goal is to gather data t…

This University of Iowa study aims to understand if people who carry a cystic fibrosis gene are at higher risk for dehydration and heat-related problems. Researchers will survey 200 adults about their heat sensitivity and have 50 of them complete a supervised heat challenge in a …

This study aims to test whether new types of CT scans can effectively measure changes in bone density and bone marrow fat in people with severe asthma who take oral steroids. Researchers will compare scans from a small group of patients who take steroids to those who do not, look…

This study aims to understand why stressful childhood events are linked to poorer heart health later in life, even in young, seemingly healthy adults. Researchers will test if a single dose of a special antioxidant supplement can improve blood vessel function and the body's respo…

This study aims to understand how using e-cigarettes (vaping) affects blood vessel health and causes inflammation in young adults. Researchers will compare young people who vape regularly with those who don't, measuring blood vessel function before and after taking an anti-inflam…

This study aims to understand how brain development is affected in children and young adults with Juvenile-onset Huntington's Disease (JoHD). Researchers will follow 40 participants aged 6-30 over time, using MRI brain scans, cognitive tests, and behavioral assessments. The goal …

This study aims to find the best heel cushion setup for ankle-foot braces (AFOs) to improve daily walking. Researchers will have 40 people who use AFOs walk with different heel cushions while measuring their movement, comfort, and pain. The goal is to gather evidence to help doct…

This research aims to better understand Charcot-Marie-Tooth disease (CMT), a genetic nerve disorder. One part of the study seeks to find out why people with the same main genetic cause of CMT can have very different symptoms. The other part is searching for new, unknown genetic c…

This study aims to understand why some people with epilepsy experience dangerous breathing problems after seizures, which can lead to sudden unexpected death (SUDEP). Researchers will monitor 335 adults with epilepsy during hospital stays, testing how their bodies respond to incr…