Hidden heat risk: one copy of CF gene may raise danger

NCT ID NCT06847256

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether people who carry one copy of the cystic fibrosis gene (but don't have the disease) are more likely to get dehydrated or have heat-related problems. Researchers will compare 100 carriers with 100 non-carriers using surveys and a 45-minute sauna challenge. The goal is to understand if this genetic trait affects how the body handles heat.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help identify people who are more prone to heat-related illness, leading to better prevention advice.

What could go wrong

This is an early observational study with only 200 participants. It does not test a treatment, so results may not lead to immediate changes in care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Dehydration exercise-induced malignant hyperthermia Heat Stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Iowa Health Care

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••