Exercise-induced malignant hyperthermia
MONDO:0018752Also known as: Exertional heat stroke
9 clinical trials for this condition and its sub-types.
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New cooling protocol could save lives in heat stroke emergencies
Disease control Recruiting nowThis study tests a new early in-hospital temperature management protocol for heat stroke patients. The protocol includes early identification, rapid cooling methods, and precise temperature monitoring. Researchers aim to see if this approach improves cooling rates and reduces dea…
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Can a cooling blanket beat heat stroke faster?
Symptom relief Recruiting nowThis study tests whether a cooling blanket helps people with heat stroke cool down faster than standard methods like ice packs and cool fluids. About 126 adults with heat stroke will be randomly assigned to receive either the cooling blanket or usual care. The goal is to see if t…
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Can you think and move in extreme heat? new study investigates
Knowledge-focused Recruiting nowThis pilot study looks at how heat stress and fatigue affect a person's ability to perform two tasks at once, like walking while doing math. Ten healthy adults will walk in a heat chamber until their body temperature reaches 39°C, then complete balance and memory tests. The goal …
Phase: NA • Sponsor: Louisiana State University Health Sciences Center Shreveport • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Army researchers hunt for heat stroke warning signs in soldiers
Knowledge-focused Recruiting nowThis study observes 150 military personnel during high-risk training events like ruck marches and timed runs to understand heat stress. Researchers will collect blood, urine, and body temperature data before, during, and after exercise. The goal is to find biomarkers that could p…
Sponsor: United States Army Research Institute of Environmental Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Hidden heat risk: one copy of CF gene may raise danger
Knowledge-focused Recruiting nowThis study looks at whether people who carry one copy of the cystic fibrosis gene (but don't have the disease) are more likely to get dehydrated or have heat-related problems. Researchers will compare 100 carriers with 100 non-carriers using surveys and a 45-minute sauna challeng…
Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Creatine supplement may shield kidneys and mind during hot workouts
Knowledge-focused Recruiting nowThis study looks at whether taking creatine for a week can reduce kidney injury and keep thinking sharp during exercise in the heat. Twenty healthy, active adults will cycle in a hot room after taking creatine or a placebo. Researchers will measure urine markers of kidney stress …
Phase: NA • Sponsor: University of Northern Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC