University Of Iowa

This study tests whether a wearable bioimpedance wristband (like a fitness tracker) helps people with severe obesity and knee osteoarthritis improve their body composition—gaining muscle and losing fat—before joint replacement surgery. All participants receive coaching on body co…

This trial investigates whether combining two drugs, niraparib and dostarlimab, with a short course of radiation before surgery can help treat locally advanced rectal cancer. The study first finds a safe dose of niraparib, then checks how well the combination shrinks the tumor. P…

This study looked at whether using a combination of weight-loss medications could help people with obesity lose weight and improve the health of their blood vessels. It involved 128 adults aged 40-75 who were obese and had at least one heart risk factor. The study was stopped ear…

This study aimed to see if special CT scans could detect changes in bone density and bone marrow in people with asthma who take oral steroids. Only 2 people took part before the study was stopped early. The results are too limited to draw any conclusions.

This study aimed to see if ultrasound could detect early changes in bone and gum after a tooth is pulled and an implant is placed right away. Some people also got a soft tissue graft to improve healing. The study was stopped early, but it planned to follow 31 adults for 6 months …