University Of Iowa
Clinical trials sponsored by University Of Iowa, explained in plain language.
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New medication plan aims to cut fall risk for rural seniors
Disease control CompletedThis study tested a medication care plan to reduce falls in adults aged 60 and older living in rural Iowa. Participants worked with a health coach to safely reduce or stop taking medications that increase fall risk. The study compared fall rates between those who received the pla…
Phase: NA • Sponsor: University of Iowa • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Can a smart monitor catch dangerous low blood sugar in new moms?
Disease control CompletedThis study tested whether using a continuous glucose monitor (CGM) in the hospital right after childbirth could better detect low blood sugar (hypoglycemia) in women with type 1 or type 2 diabetes, compared to standard finger-stick tests. Thirty-nine women in their third trimeste…
Phase: NA • Sponsor: University of Iowa • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Talking therapy may ease veterans' post-surgery pain
Symptom relief CompletedThis study tested whether a short behavioral program called Acceptance and Commitment Therapy (ACT) could reduce pain and improve function in veterans at risk for persistent pain after knee replacement. 402 veterans were randomly assigned to ACT or an attention control group. Res…
Phase: NA • Sponsor: University of Iowa • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Shoulder surgery recovery: online PT may be just as good as In-Person
Symptom relief CompletedThis study looked at whether doing physical therapy online (telerehabilitation) works as well as going to a clinic in person after shoulder replacement surgery. 93 patients were randomly assigned to either online or in-person therapy. Researchers measured shoulder movement, pain,…
Phase: NA • Sponsor: University of Iowa • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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New denture gels aim to ease dry mouth and boost comfort for seniors
Symptom relief CompletedThis study tested two over-the-counter gels placed under removable dentures to see if they improve comfort, retention, and dry mouth symptoms. 67 adults aged 18-99 with dentures made at the University of Iowa participated. Participants rated their comfort and denture fit on a sca…
Phase: NA • Sponsor: University of Iowa • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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New study reveals best timing for dental implants after tooth extraction
Knowledge-focused CompletedThis study followed 39 people who needed a tooth pulled and replaced with a dental implant. After extraction, the socket was filled with a bone graft material called Bio-Oss Collagen. Researchers then placed implants at 3, 6, or 9 months later to see how the bone healed over time…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Habit hack: worksheet boosts Pill-Taking in heart and depression patients
Knowledge-focused CompletedThis study tested whether a habit-building worksheet and a chat with a pharmacist could help people remember to take their new long-term medications for heart disease or depression. Thirty-three adults who were starting a new chronic pill took part. The goal was to see if the wor…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Can a special brace stop ankle arthritis after a break?
Knowledge-focused CompletedThis study tested whether custom carbon fiber braces can reduce harmful forces on the ankle joint after a fracture, which may lower the risk of developing arthritis. Twenty-two adults with healed ankle fractures walked with and without different brace designs while researchers me…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Carbon fiber braces could ease ankle strain, early study suggests
Knowledge-focused CompletedThis study tested custom carbon fiber ankle braces in 9 healthy adults to see how they change forces across the ankle joint. Researchers varied the brace design and used a computer model to estimate joint contact stress. The goal was to improve the model and understand how brace …
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Texting study reveals how COVID-19 symptoms change day by day
Knowledge-focused CompletedThis study followed 214 people who tested positive for COVID-19. Participants received daily text messages asking about their symptoms, like fever, cough, and loss of taste or smell. The goal was to learn how symptoms develop and vary throughout the day, helping researchers bette…
Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:15 UTC
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Which brace cuff is best? small study tests comfort and performance
Knowledge-focused CompletedThis study tested four different cuff designs for carbon fiber ankle-foot orthoses (braces) in 35 healthy adults and people with ankle arthritis or injury. Researchers measured comfort, pain, foot pressure, and walking mechanics to see which cuff design people liked best. The goa…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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New scale aims to better track nerve disease in kids
Knowledge-focused CompletedThis study created and tested a new scale called the CMT Pediatric Scale to measure symptoms and physical function in children with Charcot-Marie-Tooth disease. Researchers enrolled 500 children under 21 with CMT types 1, 2, or 4 at multiple centers. The scale assesses foot and h…
Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Survey reveals hidden psychological factors behind vaccine choices
Knowledge-focused CompletedThis completed study surveyed 1,786 US adults to understand which psychological traits—like needle fear, distrust, or open-mindedness—are most strongly linked to vaccine attitudes and history. Participants answered questions online about their feelings toward vaccines and which a…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:29 UTC