Talking therapy may ease veterans' post-surgery pain

NCT ID NCT03965897

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a short behavioral program called Acceptance and Commitment Therapy (ACT) could reduce pain and improve function in veterans at risk for persistent pain after knee replacement. 402 veterans were randomly assigned to ACT or an attention control group. Researchers tracked pain, function, anxiety, and depression for 6 months after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Acceptance and Commitment Therapy (ACT) - a brief behavioral intervention

What this could lead to

If it works, this could offer a non-drug way to help veterans recover better after knee surgery, reducing pain and improving daily function.

What could go wrong

This is a completed study, but results may not apply to all patients. The intervention is behavioral, so benefits depend on individual engagement and may not be dramatic.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Depression depressive disorder osteoarthritis, knee Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Iowa City VAMC

    Iowa City, Iowa, 52242, United States