New study reveals best timing for dental implants after tooth extraction
NCT ID NCT03659617
First seen Jun 24, 2026 · Last updated Sep 04, 2026 · Updated 3 times
Summary
This study followed 39 people who needed a tooth pulled and replaced with a dental implant. After extraction, the socket was filled with a bone graft material called Bio-Oss Collagen. Researchers then placed implants at 3, 6, or 9 months later to see how the bone healed over time. The goal was to learn the best timing for implant placement to ensure long-term success.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Bio-Oss Collagen (xenograft bone graft material)
- What this could lead to
- If successful, this could help dentists better time dental implant placement after tooth extraction, improving long-term implant success.
- What could go wrong
- This is a small, observational study with no control group, so results may not apply to all patients. The graft material is already in use, so no major new risks are expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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42 people
The number who actually took part.
- Started
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Dec 2018
- Finished
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May 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 95 years
- Sex
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Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * May be either male or female * Age: 18 years or older * Subjects with a single-rooted tooth (except mandibular incisors) indicated for extraction * Extractions socket walls should either be intact or have no more than one bony wall (buccal or lingual) dehiscence extending no more than 50% of the total bony wall height * Must be in adequate physical and mental health to undergo routine dental treatment including the surgical procedures associated tooth extraction and implant placement * Subjects' treatment plan must include replacement of the tooth to be extracted with dental implant supported fixed restoration * Subjects must have read, understood and signed an informed consent form Exclusion Criteria: * Mandibular incisors * Acute infection associated with the tooth to be extracted or with adjacent teeth * History of significant heart, stomach, liver, kidney, blood, immune system disease, or other organ impairment or systemic diseases that would prevent undergoing the proposed treatment or may result in compromised healing (e.g. poorly controlled diabetes, active heavy tobacco use \[\>10 cigs/day\]) * Subjects with uncontrolled and/or severe metabolic bone diseases or disorders, such as osteoporosis, thyroid disorders or Paget's disease * Subjects taking any medication or supplement known to largely influence bone metabolism, such as IV bisphosphonates, long-term history of oral bisphosphonates or chronic intake of glucocorticoids * Pregnant women or nursing mothers * Subjects that are unwilling or unable to sign the informed consent * History of lack of compliance with dental visits * Subjects unwilling to return for the required number of visits
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The University of Iowa College of Dentistry and Dental Clinics
Iowa City, Iowa, 52242, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Tooth-Enamel gel may boost dental implant healing
- A custom-shaped healing cap may keep gums and bone in better shape after tooth extraction and implant placement