University Of Iowa
Clinical trials sponsored by University Of Iowa, explained in plain language.
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Could a strict diet reverse a silent liver killer?
Disease control OngoingThis study is testing if an 8-week, very low-calorie meal replacement diet can reduce harmful fat and scarring in the livers of people with obesity and non-alcoholic fatty liver disease (NAFLD). Researchers will compare 10 people on the special diet to 10 others on a standard low…
Phase: NA • Sponsor: University of Iowa • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Spinal curve showdown: casts vs braces for toddlers
Disease control OngoingThis study compares two common non-surgical treatments for young children with early-onset scoliosis: serial casting and full-time bracing. Researchers are following 71 children under age 3 to see which treatment better controls spinal curve progression and improves quality of li…
Phase: NA • Sponsor: University of Iowa • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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Pharmacy on the phone: new study tests remote support to kick the habit
Disease control ENROLLING_BY_INVITATIONThis study is testing if regular phone check-ins with a pharmacist can help people quit smoking. It involves 100 current smokers who are already getting screened for lung cancer. One group will get weekly phone support for 12 weeks, while the other group will just fill out survey…
Phase: NA • Sponsor: University of Iowa • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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High-Tech braces aim to stop arthritis before it starts
Disease control TerminatedThis study aimed to see if custom-made carbon fiber braces could reduce stress on the ankle joint after a serious fracture. The goal was to prevent or delay the development of painful arthritis, a common long-term problem after such injuries. Researchers planned to test two diffe…
Phase: NA • Sponsor: University of Iowa • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Can a simple video stop Kids' cavities before they start?
Prevention OngoingThis study is testing whether special educational videos can help prevent cavities in young children. Researchers are working with 634 pregnant mothers enrolled in the WIC nutrition program, following them and their children until the child turns 3 years old. The study compares t…
Phase: NA • Sponsor: University of Iowa • Aim: Prevention
Last updated Apr 01, 2026 23:41 UTC
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Can home workouts help women recover from endometrial cancer?
Symptom relief OngoingThis study is testing whether a 10-week home exercise program can help women who have finished treatment for endometrial cancer. Researchers want to see if the program improves physical fitness, strength, and overall well-being. The program includes guided workouts and remote coa…
Phase: NA • Sponsor: University of Iowa • Aim: Symptom relief
Last updated Apr 01, 2026 23:41 UTC
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Could a Toothpaste-Like gel make dentures more comfortable?
Symptom relief ENROLLING_BY_INVITATIONThis study is testing if applying a product called MI Paste under an upper denture for two weeks can make the denture feel more comfortable and secure, and if it changes the types of bacteria and fungus in the mouth. Researchers at the University of Iowa are enrolling 50 people a…
Phase: NA • Sponsor: University of Iowa • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Major study aims to map the best path for treating rare tumors
Knowledge-focused OngoingThis study aims to understand how different treatment sequences affect the quality of life and symptoms of people with neuroendocrine tumors (NETs). Researchers will follow over 2,500 patients for up to five years, linking their survey answers about their health and treatment exp…
Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Tiny skin patches tested to boost drug delivery
Knowledge-focused OngoingThis study aims to understand how a small patch with microscopic needles affects how a common antibiotic drug gets absorbed through the skin when applied as a gel versus a cream. Researchers are testing 24 healthy volunteers to measure drug levels in their blood over several days…
Phase: PHASE4 • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Home bladder monitor could replace clinic visits
Knowledge-focused OngoingThis study is testing whether patients or caregivers can use a new portable device at home to measure bladder pressure. The device attaches to standard catheters and has already shown accurate readings in clinic settings. Researchers want to see if 30 patients with nerve-related …
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:24 UTC