University Of Iowa

This study compares two treatments—casting and bracing—for young children (up to age 3) with idiopathic early-onset scoliosis, a condition where the spine curves. The goal is to see which method better slows curve progression or corrects it, while also tracking quality of life. A…

This study tests whether a very low-calorie diet (800-960 calories per day) can reduce liver fat and scarring in 20 adults with obesity and non-alcoholic fatty liver disease (NAFLD). Participants follow the diet for 8 weeks, and researchers measure liver changes using a special u…

This study tests whether a special video program for pregnant mothers can help prevent early childhood cavities. Researchers will enroll 634 pregnant women from the WIC program and follow their children until age 3. The program uses motivational videos to encourage healthy oral h…

This study looks at whether a 10-week exercise program done at home can improve physical fitness in women who have finished treatment for endometrial cancer. Ten participants will follow a guided exercise plan and be tested on strength, balance, and endurance. The goal is to see …

This study looks at whether talking to a pharmacist over the phone can help smokers quit. About 80 people who are current smokers and in a lung cancer screening program will take part. One group gets regular phone calls with a pharmacist for 12 weeks, while the other group just f…

This study looks at whether fish oil, alone or with the drug salsalate, can improve blood markers of inflammation in people with type 2 diabetes and diabetic nerve pain (neuropathy). About 100 adults will take fish oil capsules for 4 months, then add salsalate tablets for 2 more …

This study tests a new device called a cystoelastometer that connects to a standard urinary catheter to measure bladder pressure at home. It involves 30 people with neurogenic bladder who already use catheters. The goal is to see how well patients and caregivers can use the devic…

This study was designed to see if custom carbon fiber braces can reduce pressure on the ankle joint after a fracture, potentially lowering the risk of developing arthritis. Researchers planned to test the braces on adults with healed ankle fractures by measuring forces and pain d…

This study follows 37 children and young adults with Juvenile-onset Huntington's disease (JoHD) over time. Researchers use brain scans, thinking tests, and behavior checklists to see how the disease affects the brain differently than adult-onset Huntington's. The goal is to find …

This study looks at whether MI Paste, a common over-the-counter product for sensitive teeth, changes the types of bacteria and fungus living in the mouths of older adults who wear dentures. Researchers will also check if the paste makes dentures more comfortable and fit better. A…

This study looks at very small premature babies (weighing 2.2 pounds or less) to understand why some develop low blood pressure in their first week of life. Researchers will monitor heart and lung changes in babies with and without low blood pressure. The goal is to learn more ab…

This study looks at how a micropatch affects the way metronidazole (a common antibiotic) enters the body through the skin. Twenty-four healthy adults will have either a gel or cream form applied to micropatch-treated skin. Researchers will measure drug levels in the blood to see …

This study follows over 2,500 people with neuroendocrine tumors (NETs) to learn how symptoms and treatments affect their quality of life. Participants fill out surveys about their well-being and care experiences for up to 18 months. The goal is to find which treatments work best …