Fish oil and Aspirin-Like drug may ease diabetic nerve pain

NCT ID NCT05169060

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests whether fish oil, alone or with salsalate (an anti-inflammatory drug), can improve blood markers linked to nerve health in people with type 2 diabetes and diabetic neuropathy. About 100 adults will take fish oil capsules for 4 months, then add salsalate for 2 more months. The goal is to see if this combination safely increases anti-inflammatory substances in the blood, which could eventually lead to a treatment for nerve damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fish oil and salsalate

What this could lead to

If it works, this could point toward a new treatment for diabetic nerve pain and damage.

What could go wrong

This is a very early, small study (100 people) looking at blood markers, not symptoms. The combination may not actually help nerve pain or could cause side effects like stomach issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus diabetic neuropathy Inflammation type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Oregon Health Science University

    Portland, Oregon, 97239, United States

  • University of Iowa

    Iowa City, Iowa, 52241, United States