Brain scans track rare childhood Huntington's disease
NCT ID NCT05707663
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study follows 37 children and young adults with juvenile-onset Huntington's disease (JoHD) to understand how their brains develop differently from adult-onset cases. Participants undergo cognitive tests, behavioral assessments, and MRI scans over time. The goal is to find reliable brain-based markers that could help monitor the disease in future research.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify reliable brain-based biomarkers for juvenile Huntington's disease, helping future research track disease progression more accurately.
- What could go wrong
- This is a small observational study (37 participants) that does not test any treatment. It may not yield clear biomarkers due to the rarity and variability of juvenile-onset HD.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for JUVENILE HUNTINGTON DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Children's Hospital of Philadelphia with the University of Pennsylvania
Philadelphia, Pennsylvania, 19146, United States
-
University of California Davis
Sacramento, California, 95817, United States
-
University of Iowa Hospitals and Clinics, Department of Psychiatry
Iowa City, Iowa, 52242, United States
-
University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
-
Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States