Childhood trauma linked to heart risk: can a supplement help?

NCT ID NCT07244809

Recruiting now Knowledge-focused Sponsor: University of Iowa Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether early life adversity (like abuse or neglect) damages blood vessel function in young adults ages 18-29. Researchers will give participants a single dose of MitoQ, a supplement that targets cell energy centers, to see if it reduces stress-related damage. The goal is to understand the biological link between childhood stress and future heart disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Mitoquinone mesylate (MitoQ) dietary supplement
What this could lead to: If successful, this could point toward a way to reduce cardiovascular risk in people who experienced childhood adversity.
What could go wrong: This is an early pilot study with a single dose of supplement, so results may not translate to long-term benefits or apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVERSE CHILDHOOD EXPERIENCE ENDOTHELIAL FUNCTION (FMD) ENDOTHELIAL INJURY MITOCHONDRIAL FUNCTION OXIDATIVE STRESS PSYCHOSOCIAL INFLUENCE ON CARDIOVASCULAR DISEASE

Contacts and locations

Locations

Integrative Laboratory of Applied Physiology and Lifestyle Medicine
RECRUITING

Iowa City, Iowa, 52242, United States

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