Gut sugar test may predict who loses most weight after surgery

NCT ID NCT05408728

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether the way your gut absorbs sugar can predict how much weight you lose after bariatric surgery. Researchers will take small tissue samples from the intestine before and one year after surgery in 52 obese patients. They will check for changes in sugar absorption and gene activity to see if these factors are linked to weight loss success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict which patients will lose the most weight after bariatric surgery, leading to more personalized treatment plans.
What could go wrong: This is a small, early-stage observational study, not a treatment trial. It may not find a clear link between sugar absorption and weight loss, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BARIATRIC SURGERY CANDIDATE HEALTHY OBESE

Contacts and locations

Locations

Mayo Clinic Florida

Jacksonville, Florida, 32224, United States

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Other studies related to the condition(s) this trial covers.