BARIATRIC SURGERY CANDIDATE

This study compares three types of weight-loss surgery to the best medical care for helping people with type 2 diabetes achieve long-term remission. About 408 severely obese adults with diabetes will be followed to see which approach works best for controlling blood sugar and imp…

This study looks at people who had a sleeve gastrectomy but regained weight. It compares three different follow-up surgeries to see which one helps them lose the most weight with the fewest side effects. The goal is to find the best option for long-term weight control and better …

This study compares bariatric surgery to standard medical weight management in 200 adults with severe obesity (BMI 30 or higher) and high-risk cardiovascular disease. The goal is to see if surgery reduces major heart problems like heart attacks, strokes, and heart failure hospita…

This study tests a remote behavioral program for people who have regained at least 5% of their weight after bariatric surgery. 200 participants will either receive the program or standard advice. The goal is to see if the program helps reverse weight regain and improve eating hab…

This study looks at whether a special diet workshop held 15 days after bariatric surgery can help patients increase their protein intake over the next year. About 88 adults who are scheduled for sleeve gastrectomy or bypass surgery will take part. The goal is to improve protein l…

This study tests whether avoiding opioids during weight-loss surgery can still control pain effectively. About 70 adults having sleeve gastrectomy will receive either opioid-free anesthesia (using a mix of other drugs) or standard opioid-based anesthesia. Researchers will measure…

This study compares ready-to-eat very low calorie meals to standard liquid meal replacements for people preparing for bariatric surgery. The goal is to see if the ready-to-eat option improves how well patients stick to their diet, measured by blood ketones and meal logging. About…

This study compares two types of weight-loss surgery—robotic and laparoscopic sleeve gastrectomy—to see which causes less pain the day after surgery. About 91 adults who qualify for weight-loss surgery will be randomly assigned to one of the two procedures. The main goal is to me…

This study uses advanced heart MRI to see how bariatric surgery and cardiac rehabilitation change the heart's structure and function. Researchers will scan 150 adults before and 6-12 months after these metabolic interventions. The goal is to understand how these treatments affect…

This study creates a registry to collect information on endoscopic bariatric therapies (EBTs), which are non-surgical procedures for weight loss. Researchers will review medical charts and follow up to 9,999 participants for one year to measure weight changes and track any side e…

This study follows 1000 people who had bariatric surgery 5 years ago to understand why some maintain weight loss while others do not. Researchers will track weight, surgery type, and other factors to identify predictors of success. The goal is to help doctors and patients choose …

This study looks at 100 people having weight-loss surgery to find out which method of reopening the lungs after anesthesia is safer and more effective. Participants will receive one of two lung recruitment techniques at the end of surgery. The goal is to see which approach leads …

This study follows 300 people having metabolic (weight-loss) surgery to see how their gut bacteria change over time and how those changes relate to improvements in heart health, diabetes, and cholesterol. Participants provide stool, blood, and tissue samples before and up to 3 ye…

This study looks at the nutritional effects of a low-calorie, high-protein diet given to people before they have weight-loss (bariatric) surgery. The goal is to see if this diet causes any health problems like low blood cell counts, vitamin deficiency, or muscle weakness. About 2…

This study looks at how diet and sex influence the chance of developing kidney stones after gastric bypass surgery. About 28 people who are approved for surgery will eat a special diet for six days and visit the clinic three times. Researchers will measure urine changes to unders…

This study looks at how two different anesthesia methods affect stress during weight-loss surgery. About 70 adults having sleeve gastrectomy or gastric bypass will receive opioid-free anesthesia, some with and some without the gas desflurane. Researchers will measure stress hormo…

This study looks at how high-intensity interval training (HIIT) changes brain activity and appetite in people who regained weight after bariatric surgery. Researchers will use brain scans and questionnaires to understand the connection between exercise, brain function, and weight…