Can bariatric surgery save hearts? major trial aims to find out
NCT ID NCT05531474
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether bariatric surgery (like gastric bypass) can safely reduce the risk of major heart problems—such as heart attacks, strokes, and heart failure—in people with severe obesity and high heart risk. About 700 participants will be randomly assigned to either surgery or standard medical weight management. The trial also looks at effects on mental health, thinking skills, and cost-effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bariatric surgery (gastric bypass, sleeve gastrectomy, or duodenal switch)
What this could lead to
If it works, this could show that bariatric surgery is a safe and effective way to lower the chance of major heart problems in people with severe obesity and existing heart disease.
What could go wrong
This is a large, ongoing trial, but surgery carries risks like infection or complications. Results may not apply to everyone, and the benefit over medical weight management is not yet proven.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hamilton Health Sciences
RECRUITINGHamilton, Ontario, L8L 2X2, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••