Can a second bypass surgery rescue failed weight loss?
NCT ID NCT04165694
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study looks at whether a follow-up surgery called Single Anastomosis Duodenal Ileal Bypass (SADI) can help people who had a sleeve gastrectomy but didn't lose enough weight. Participants are adults with severe obesity who lost less than 10% of their body weight after the first surgery. The goal is to see if this second procedure leads to more weight loss and improves obesity-related health problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Single Anastomosis Duodenal Ileal Bypass (SADI), a surgical procedure that reroutes the intestine to reduce calorie absorption
- What this could lead to
- If successful, this could offer a reliable second-step surgery for people with severe obesity who didn't lose enough weight after a sleeve gastrectomy, potentially improving weight loss and related health conditions.
- What could go wrong
- This is a relatively small study, and the procedure carries surgical risks like any major operation. Results may not apply to all patients, and long-term benefits are still uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kaiser Permanente Southern California West Los Angeles Medical Center
Los Angeles, California, 90034, United States
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