Pre-Surgery diet could shrink liver and boost safety for obesity patients

NCT ID NCT04942093

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether a 4-week low-calorie, high-protein diet before bariatric surgery is safe and well-tolerated. Researchers want to see if it reduces liver fat and helps surgeons operate more easily. About 200 people with severe obesity will be split into two groups: one follows the diet, the other does not. The main focus is on side effects like low blood counts, vitamin deficiency, or muscle weakness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

low-calorie, high-protein diet

What this could lead to

If successful, this diet could become a standard short-term preparation before obesity surgery, making the procedure safer and easier for surgeons.

What could go wrong

This is a small, early-stage study focused on safety and tolerance, not on long-term weight loss. The diet may cause side effects like low blood counts or muscle weakness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Obesity, Abdominal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de ROUEN

    RECRUITING

    Rouen, 76 000, France

    Contact Email: •••••@•••••

  • Ch Dieppe

    RECRUITING

    Dieppe, France

    Contact Email: •••••@•••••

  • HPE

    RECRUITING

    Le Havre, France

    Contact Email: •••••@•••••