Exercise may rewire the brain to fight weight regain after surgery

NCT ID NCT06511310

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether high-intensity interval training (HIIT) can change how the brain works in people who have regained weight after bariatric surgery. Researchers will use brain scans and questionnaires to measure changes in brain connectivity, appetite, and mood. The goal is to understand the link between exercise, brain function, and weight control, which could inform future obesity treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

High Intensity Interval Training (HIIT)

What this could lead to

If it works, this could point toward exercise-based strategies to help people maintain weight loss after bariatric surgery.

What could go wrong

This is a very small, early-stage study with only 15 participants, so results may not apply to everyone. It is designed to gather information, not to test a treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Appetitive Behavior Obesity obesity disorder Weight Gain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Joslin Diabetes Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••