Exercise may rewire the brain to fight weight regain after surgery

NCT ID NCT06511310

Recruiting now Knowledge-focused Sponsor: Joslin Diabetes Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether high-intensity interval training (HIIT) can change how the brain works in people who have regained weight after bariatric surgery. Researchers will use brain scans and questionnaires to measure changes in brain connectivity, appetite, and mood. The goal is to understand the link between exercise, brain function, and weight control, which could inform future obesity treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: High Intensity Interval Training (HIIT)
What this could lead to: If it works, this could point toward exercise-based strategies to help people maintain weight loss after bariatric surgery.
What could go wrong: This is a very small, early-stage study with only 15 participants, so results may not apply to everyone. It is designed to gather information, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Appetitive Behavior Obesity obesity disorder Weight Gain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APPETITIVE BEHAVIOR BARIATRIC SURGERY CANDIDATE OBESITY WEIGHT GAIN

Contacts and locations

Locations

Joslin Diabetes Center
RECRUITING

Boston, Massachusetts, 02215, United States

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