BARIATRIC SURGERY CANDIDATE

This study is testing whether bariatric surgery (like gastric bypass) can safely reduce the risk of major heart problems—such as heart attacks, strokes, and heart failure—in people with severe obesity and high heart risk. About 700 participants will be randomly assigned to either…

This study tests a remote behavioral program for people who have regained at least 5% of their weight after bariatric surgery. 200 participants will be randomly assigned to either the program or a control group that receives standard dietary advice. The goal is to see if the prog…

This study compares three types of weight-loss surgery (sleeve gastrectomy, gastric bypass, and duodenal switch) with standard medical care for people with type 2 diabetes and a BMI of 35 or higher. The goal is to see which approach leads to long-term diabetes remission and impro…

This study follows 234 people who regained weight after a sleeve gastrectomy and are now getting a revision surgery. The goal is to compare three procedures—SADI-S, RYGB, and OAGB—to see which leads to the most weight loss, fewest complications, and best nutritional outcomes. Par…

This study tests if a mild electrical patch placed on the skin (called TENS) can prevent breathing problems after weight-loss surgery in people with severe obesity. About 70 participants will be randomly assigned to receive either TENS or a fake device. The main goal is to see if…

This study looks at two ways to manage pain during weight-loss surgery (sleeve gastrectomy) in 70 adults. One group gets standard opioid painkillers, the other gets a mix of non-opioid drugs. The goal is to see if the opioid-free approach can reduce opioid use and still control p…

This study looks at whether a special diet workshop held 15 days after bariatric surgery can help patients increase their protein intake. About 88 adults who are scheduled for weight-loss surgery will take part. The goal is to improve protein levels and overall recovery over the …

This study compares two types of weight-loss surgery—robotic sleeve gastrectomy and laparoscopic sleeve gastrectomy—to see which causes less pain right after the operation. About 91 people having sleeve gastrectomy at Cleveland Clinic will be randomly assigned to one method. Rese…

This study looks at whether a 4-week low-calorie, high-protein diet before bariatric surgery is safe and well-tolerated. Researchers want to see if it reduces liver fat and helps surgeons operate more easily. About 200 people with severe obesity will be split into two groups: one…

This study compares two pre-surgery diets for people scheduled for bariatric surgery: ready-to-eat meals versus standard liquid meal replacements. The goal is to see which diet is easier to stick to, measured by blood ketone levels and meal logging. About 140 adults will particip…

This study follows 750 severely or morbidly obese patients who have undergone bariatric surgery at a single hospital in France. Researchers aim to track long-term weight loss and improvements in related health issues such as diabetes and high blood pressure. By observing real-wor…

This study follows 1,000 people who had bariatric surgery 5 years ago to learn why some maintain significant weight loss while others do not. Researchers will track weight, type of surgery, and other factors to improve patient counseling and tailor surgical choices. The goal is t…

This study aims to understand why some people develop kidney stones after gastric bypass surgery. Researchers will look at how diet and sex influence urine chemistry. About 28 participants who are scheduled for bariatric surgery will follow a special diet for six days and provide…

This study uses advanced heart MRI to see how bariatric surgery and cardiac rehabilitation change the heart's structure and function. Researchers will scan 150 adults before and 6-12 months after these metabolic treatments. The goal is to understand how the heart adapts to these …

This trial tests two types of opioid-free anesthesia in 70 people having weight-loss surgery. One method uses a gas called desflurane, the other uses intravenous drugs. Researchers will measure stress hormones in the blood to see which approach causes less stress on the body. The…

This study collects information from medical records and patient visits to see how well endoscopic bariatric therapies (EBTs) work for weight loss and if they are safe. It includes adults who have had or plan to have an EBT within six months. The goal is to track weight changes a…

This study tests two different methods to reopen collapsed lung areas after weight-loss surgery. One hundred patients having laparoscopic bariatric surgery will receive either a sustained inflation or a stepwise PEEP technique. The goal is to see which method improves oxygen leve…

This study follows 300 people who are having weight-loss (metabolic) surgery to see how their gut bacteria change over time and how those changes relate to heart health, diabetes, and cholesterol. Participants provide blood and stool samples before surgery and at several follow-u…

This study looks at whether high-intensity interval training (HIIT) can change how the brain works in people who have regained weight after bariatric surgery. Researchers will use brain scans and questionnaires to measure changes in brain connectivity, appetite, and mood. The goa…