Gut bacteria may hold key to better heart health after Weight-Loss surgery

NCT ID NCT05000996

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 300 people who are having weight-loss (metabolic) surgery to see how their gut bacteria change over time and how those changes relate to heart health, diabetes, and cholesterol. Participants provide blood and stool samples before surgery and at several follow-up visits for up to 3 years, with long-term health tracked for up to 10 years. The goal is to learn how gut bacteria might improve surgical outcomes, especially in African Americans who are at higher risk for heart disease.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vanderbilt_University MC

    RECRUITING

    Nashville, Tennessee, 37232, United States

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