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Brain zapping study aims to tweak Decision-Making

NCT ID NCT05917002

Knowledge-focused Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study was designed to see if a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) could temporarily alter how healthy people make rational decisions. Participants would have undergone two sessions of either real or sham stimulation while their impulsivity was measured. However, the study was withdrawn before any participants were enrolled, so no data was collected.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS) device
What this could lead to
If successful, this study could point toward ways to use brain stimulation to improve decision-making in people with certain mental health conditions.
What could go wrong
This is a very early, small study in healthy volunteers, not patients. It was withdrawn before enrolling anyone, so no results are available. The approach is experimental and may not translate to real-world benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Started

Aug 2025

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Is able to read consent document and provide informed consent * English is first or primary language Exclusion Criteria: * • Current psychiatric disorder (as defined by DSM-5 and determined using standardized self-report instruments) * Suicide attempt in the past year * Lifetime diagnosis of psychotic disorder or bipolar mania * Presence of neurological disorder that contraindicates TMS or neurophysiological recording: * Seizure disorder * Lifetime history of traumatic brain injury with loss of consciousness * Neurodegenerative disorder (e.g., Alzheimer's Disease, Parkinson's Disease, Frontotemporal Dementia) * Presence of standard contraindications for rTMS * Currently pregnant * Significant sensitivity to noise * Medical treatments or conditions that lower seizure threshold * History of severe brain injury * History of seizures/epilepsy * Currently taking chronic opiate medications or substances * Inability or unwillingness of subject to give informed consent

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

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