Timing aspirin might counteract blood pressure side effect of common painkiller

NCT ID NCT03590821

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase study tests whether taking a low-dose aspirin in the evening can offset the blood pressure increases caused by the pain reliever celecoxib. Researchers will monitor blood pressure in 60 healthy adults over several weeks. The goal is to learn if timing matters for managing side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Aspirin and celecoxib
What this could lead to
If successful, this could point toward a way to manage blood pressure side effects from common pain relievers like celecoxib.
What could go wrong
This is a very early, small study in healthy people, so results may not apply to patients with chronic conditions or predict real-world outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

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