New HPV vaccine aims to shield against extra cancer types

NCT ID NCT07224477

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests V540A, an experimental vaccine designed to protect against 9 HPV types already covered by Gardasil 9, plus additional unique types. About 525 healthy women aged 16-26 will receive either V540A or Gardasil 9 to compare safety and immune response. The goal is to see if V540A can offer broader protection against HPV-related cancers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
V540A (experimental HPV vaccine)
What this could lead to
If successful, V540A could provide broader protection against HPV-related cancers by covering more virus types than current vaccines.
What could go wrong
This is an early phase 2 trial, so safety and immune response are still being tested. It may not prove more effective than existing vaccines, and side effects like injection-site pain are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEALTHY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.