Malaria drug combo safety checked in tiny study
NCT ID NCT04080895
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This early-stage study aimed to see how two common malaria drugs, artemether-lumefantrine and amodiaquine, interact in the body. It enrolled only 8 healthy adults in Thailand and was terminated early. The goal was to measure drug levels and safety when given alone or together.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- artemether-lumefantrine and amodiaquine
- What this could lead to
- If successful, this could help doctors understand how to safely combine these two malaria treatments.
- What could go wrong
- This is a very early, small study in healthy people, not patients. It was terminated early, so results are limited and may not apply to real-world use.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Faculty of Tropical Medicine, Mahidol University
Bangkok, 10400, Thailand
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