Malaria drug combo safety checked in tiny study

NCT ID NCT04080895

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study aimed to see how two common malaria drugs, artemether-lumefantrine and amodiaquine, interact in the body. It enrolled only 8 healthy adults in Thailand and was terminated early. The goal was to measure drug levels and safety when given alone or together.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
artemether-lumefantrine and amodiaquine
What this could lead to
If successful, this could help doctors understand how to safely combine these two malaria treatments.
What could go wrong
This is a very early, small study in healthy people, not patients. It was terminated early, so results are limited and may not apply to real-world use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Tropical Medicine, Mahidol University

    Bangkok, 10400, Thailand

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