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Can we predict Parkinson's decades early? new study recruits 600 participants

NCT ID NCT05253560

Recruiting now Knowledge-focused Sponsor: Shaare Zedek Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find early signs of Parkinson's disease in people who carry a change in the GBA1 gene, which puts them at higher risk. Researchers will use simple, non-invasive tests to check for subtle changes in movement, thinking, sleep, and other functions that can appear up to 20 years before Parkinson's is diagnosed. The goal is to build a model that identifies who is most likely to develop Parkinson's, so they can be offered preventive treatments in the future. The study includes 600 adults aged 40-75 who are GBA1 carriers, along with healthy volunteers and people with Gaucher disease for comparison.

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Conditions

The condition(s) this trial relates to.

Gaucher disease Gaucher disease type I

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GAUCHER DISEASE, TYPE 1 HEALTHY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Michal Becker- Cohen

    RECRUITING

    Jerusalem, Please Select..., 9103102, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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