Scientists test new way to track nutrient use in bone marrow cells

NCT ID NCT03384108

Recruiting now Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This pilot study aims to see if a new method can measure how healthy bone marrow plasma cells use glutamine, an important nutrient. Twenty healthy adults will receive an intravenous infusion of a special labeled glutamine, followed by a bone marrow aspiration. The goal is to compare this in-person approach with lab-based methods, laying groundwork for future disease research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 5-13C-Glutamine (a labeled form of glutamine given intravenously)
What this could lead to: If successful, this method could help researchers understand how plasma cells use nutrients, potentially guiding future treatments for diseases like multiple myeloma.
What could go wrong: This is a very early, small pilot study in healthy people, not patients. It only tests the measurement method, not a treatment, so it may not lead directly to any therapy.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY

Contacts and locations

Locations

Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States

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