String-Attached capsule camera could replace colonoscopy for some patients

NCT ID NCT07219537

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 31 times

Summary

This pilot study tests a new device called the Retro-TCE capsule, which is a small camera attached to a string that is inserted into the lower gut to take pictures without needing sedation. The study will enroll 30 people, including healthy volunteers and those with Lynch syndrome or inflammatory bowel diseases, to see if the device can capture clear images and be tolerated comfortably. If it works, it could offer a simpler and cheaper way to check for gut diseases.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Retro-TCE capsule device

What this could lead to

If successful, this could provide a simpler, cheaper way to screen for lower GI diseases without sedation or a full colonoscopy.

What could go wrong

This is a very early pilot study with only 30 participants, so the device may not work well or be comfortable enough for wider use. It is not yet proven to replace standard colonoscopy.

Conditions

The condition(s) this trial relates to.

Colorectal Neoplasms, Hereditary Nonpolyposis Crohn disease inflammatory bowel disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.