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String-Attached capsule camera could replace colonoscopy for some patients

NCT ID NCT07219537

Recruiting now Diagnosis Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests a new device called the Retro-TCE capsule, which is a small camera attached to a string that is inserted into the lower gut to take pictures without needing sedation. The study will enroll 30 people, including healthy volunteers and those with Lynch syndrome or inflammatory bowel diseases, to see if the device can capture clear images and be tolerated comfortably. If it works, it could offer a simpler and cheaper way to check for gut diseases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Retro-TCE capsule device
What this could lead to
If successful, this could provide a simpler, cheaper way to screen for lower GI diseases without sedation or a full colonoscopy.
What could go wrong
This is a very early pilot study with only 30 participants, so the device may not work well or be comfortable enough for wider use. It is not yet proven to replace standard colonoscopy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Colorectal Neoplasms, Hereditary Nonpolyposis Crohn disease inflammatory bowel disease Lynch syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHN DISEASE HEALTHY INFLAMMATORY BOWEL DISEASES LYNCH SYNDROME

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Email: •••••@•••••

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