INFLAMMATORY BOWEL DISEASES

This study is testing whether a special nutrition program before and after bowel surgery for Crohn's disease or ulcerative colitis helps patients recover better. Researchers want to see if drinking nutritional shakes before surgery reduces hospital stays and serious complications…

This study is testing whether a special type of infrared light, applied to the abdomen, can safely reduce inflammation and symptoms in people with Crohn's disease. Researchers will compare three different intensities of light therapy against a placebo treatment in 40 participants…

This study is testing whether adding a common antifungal medication (fluconazole) to standard Crohn's disease treatments improves patient outcomes. Researchers want to see if this combination helps control symptoms better than the standard treatments alone. The trial will involve…

This study is testing whether adding fermented foods like yogurt, kefir, and kimchi to the diet can help control inflammation and improve quality of life for adults with mild to moderate ulcerative colitis. Researchers at Stanford University are enrolling 21 participants to see i…

This study is testing whether taking frozen capsules containing processed stool from healthy donors can help control active ulcerative colitis. It will involve 129 adults whose current treatments aren't working well. Participants will receive either the full stool transplant, a f…

This trial is testing whether dapagliflozin, a medication currently used for diabetes, can help control ulcerative colitis. Researchers will give the drug to 50 adults with mild-to-moderate disease to see if it reduces gut inflammation and symptoms like diarrhea and abdominal pai…

This study is testing several long-acting antibody treatments, both alone and in combinations, for adults with moderate to severe ulcerative colitis. The goal is to see if these treatments can control the disease by reducing inflammation and symptoms. The trial will involve 645 p…

This study is testing whether robotic surgery can be used effectively for people with inflammatory bowel diseases like Crohn's and ulcerative colitis. Researchers will compare robotic surgery to standard laparoscopic (keyhole) surgery in 100 patients to see which approach works b…

This study aims to see how well and how safely the drug mirikizumab works over a long period (about 3 years) in children and adolescents with moderate-to-severe ulcerative colitis or Crohn's disease. It is an extension study for about 150 young people who have already been taking…

This study is testing an experimental medication called MORF-057 for adults with moderate to severe Crohn's disease. It aims to see if the drug can reduce intestinal inflammation and improve symptoms better than a placebo. Participants will receive either the study drug or a plac…

This study is testing a new, low-cost tool to take pictures inside the lower intestines. The tool is a tiny capsule, about the size of a vitamin pill, attached to a thin string. Doctors will gently guide the capsule up the colon in awake participants to see if it can capture clea…

This study is testing a new web-based tool that gives people with a family history of Crohn's disease a personalized estimate of their own risk. Researchers want to see if receiving this risk information motivates healthy changes in diet, exercise, and smoking, and if those chang…

This study is testing whether a virtual reality (VR) program that teaches mind-body techniques can help hospitalized patients with inflammatory bowel disease (IBD) manage their pain. Researchers want to see if patients find the VR therapy practical and acceptable to use while in …

This study aims to understand how social and economic factors affect medication use and quality of life for Hispanic and Black patients with inflammatory bowel disease (IBD). Researchers will survey 400 adults with Crohn's disease or ulcerative colitis to identify barriers to pro…

This study aims to understand how a patient's nutritional status and body composition affect their treatment outcomes for Crohn's disease and ulcerative colitis. Researchers will observe 300 patients starting new medications or having surgery, measuring things like muscle mass an…

This study aims to understand what goes wrong in the immune system to cause chronic gut diseases like celiac disease and inflammatory bowel disease. Researchers will analyze blood and tissue samples from 200 adult participants to learn how immune cells become dysfunctional. The g…

This study aims to discover if patterns in a person's gut bacteria can predict how well Crohn's disease treatments will work. Researchers will collect stool, blood, and tissue samples from 100 adults with Crohn's disease in British Columbia, comparing them to people without the c…

This study aims to understand why patients develop a serious liver disease called Primary Sclerosing Cholangitis (PSC), which has no cure and often leads to cancer or transplant. Researchers will give 15 adult patients with PSC a common cholesterol-lowering drug (rosuvastatin) to…

This study aims to understand if a toxin called deoxynivalenol (DON), found in some grains, could be an environmental risk factor for developing inflammatory bowel diseases (IBD) like Crohn's. Researchers will compare samples from 100 people undergoing intestinal surgery—some wit…

This study is testing a new swallowable capsule that measures temperature inside the digestive tract. The goal is to see if this 'thermal capsule' can collect useful data that might one day help doctors spot diseases like Crohn's. Researchers are enrolling 10 healthy adults to sw…

This study aims to use artificial intelligence (AI) to analyze health data from people with Crohn's disease or ulcerative colitis (IBD) who are changing their treatment. Researchers will collect information from about 800 participants over up to five years to find patterns that c…

This study aims to create a large collection of blood samples and health information from people with autoimmune diseases like lupus and scleroderma. Researchers will use these samples to look for new biological markers that could help diagnose diseases earlier, predict how they …

This study is testing whether genetic information can help doctors choose safer and more effective medications for their patients. Researchers will collect DNA samples from 1,200 adults receiving routine care at the University of Chicago Medical Center. They will track whether do…

This study aims to create a single, large registry to collect information on many different rare diseases. It will enroll about 380 patients already being treated at the Hospital Italiano de Buenos Aires who have one of the listed rare conditions. The goal is to gather data to be…

This study aims to understand how different compounds from the cannabis plant affect immune cells in a lab setting. Researchers will collect blood from 100 patients with chronic inflammatory diseases like rheumatoid arthritis and lupus. They will test various cannabis extracts on…