Scientists hunt for clues to chronic pain in IBD — no treatment, just answers.
NCT ID NCT04995224
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is tracking over 25,000 people with inflammatory bowel disease (IBD) to understand why many continue to have abdominal pain even when their disease is in remission. Researchers will use questionnaires, blood and stool samples, heart rate recordings, and genetic data to identify risk factors. The goal is to build a model that can predict who will develop chronic pain, which could eventually lead to better prevention or treatment strategies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors predict which IBD patients are likely to develop chronic pain, and point toward new ways to prevent or manage that pain.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly test any therapy, and the findings may take years to translate into practical help for patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CROHN'S DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Neurogastroenterology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London
RECRUITINGLondon, E1 2AJ, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Sound waves vs. scope: a gentler way to spot pouch inflammation?
- Can we predict how kids with IBD will respond to treatment?
- AI reads scans to forecast Crohn's complications
- Can stem cell vesicles heal Crohn's fistulas?
- Can a new drug calm the Gut's overactive immune response in Crohn's?
- Can switching IBD meds heal the gut when symptoms are quiet?