Gut microbiome may hold key to personalized Crohn's therapy
NCT ID NCT06453720
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether the unique mix of bacteria and fungi in the gut can predict how well Crohn's disease patients will respond to treatment. Researchers will collect stool, blood, and tissue samples from 100 adults during routine colonoscopies and track their health for a year. The goal is to find microbial signatures that could one day help doctors choose the most effective therapy for each patient.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors predict which treatments will work best for individual Crohn's disease patients based on their gut microbiome.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly test a new therapy. The findings may not lead to immediate clinical changes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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GI Research Institute
RECRUITINGVancouver, British Columbia, V6Z 2K5, Canada
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