New hope for kids with tough IBD: study tests Next-Gen drugs

NCT ID NCT07198113

Recruiting now Disease control Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how well newer inflammatory bowel disease (IBD) medications work in children whose previous anti-TNF treatment stopped working or didn't help. About 1,100 kids with Crohn's disease or ulcerative colitis will answer questions about their symptoms and health over time while taking these newer drugs as part of their regular care. The goal is to see if these medications are safe and effective for children with hard-to-treat IBD.

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Conditions

The condition(s) this trial relates to.

Crohn disease indeterminate colitis inflammatory bowel disease inflammatory bowel disease 1 Pediatric ulcerative colitis ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHN DISEASE INFLAMMATORY BOWEL DISEASES ULCERATIVE COLITIS, PEDIATRIC

Contacts and locations

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Locations

Atrium Health
RECRUITING

Charlotte, North Carolina, 28203, United States

Contact Email: •••••@•••••
Duke Health System
RECRUITING

Durham, North Carolina, 27701, United States
University of North Carolina at Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27599, United States
University of Pittsburgh Medical Center, Children's Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15222, United States

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