INFLAMMATORY BOWEL DISEASES

This study is testing whether a personalized type of resistant starch (a plant-based fiber) can help improve gut health in children with Crohn's disease or ulcerative colitis. Researchers want to see if this starch can promote healthier gut bacteria and reduce inflammation. The t…

This study is testing whether a specific type of dietary starch, chosen based on a child's unique gut bacteria, can help improve their gut health while they are on standard Crohn's medication. It involves 45 children aged 8-17 who have Crohn's disease in remission or with mild sy…

This study is testing if a special, personalized type of plant-based starch can help control inflammatory bowel diseases (IBD) like Crohn's and ulcerative colitis in children. Researchers want to see if this starch, tailored to each child's gut bacteria, can reduce gut inflammati…

This study is testing an investigational oral drug called MORF-057 to see if it can help control moderate to severe ulcerative colitis. It will compare three different doses against a placebo pill in about 280 adults who haven't gotten enough relief from standard treatments. The …

This study is testing whether a smartphone app and special 'smart' labels can help people with Crohn's disease or ulcerative colitis remember to take their medication. About 123 adults starting a new pill or injection treatment will use the app for a year. The goal is to see if t…

This study is testing whether regular text message check-ins and direct messaging with a medical team helps people with Crohn's disease or ulcerative colitis feel more confident managing their condition and achieve better health outcomes. It will involve 900 teenagers and adults …

This study aims to determine whether taking fewer random tissue samples during colonoscopy is just as effective at finding precancerous growths in people with long-term inflammatory bowel disease. Researchers will compare two different biopsy approaches in over 1,600 patients und…

This study aims to create a new training and support program for nurses to help them better discuss and care for the sexual health needs of men with inflammatory bowel disease (IBD). Researchers are working directly with patients, their partners, and healthcare staff to design th…

This study is collecting long-term health information from nearly 5,000 children and teenagers with Crohn's disease, ulcerative colitis, or other inflammatory bowel diseases. Researchers will follow participants for up to 20 years to understand the safety of treatments and how th…

This study is a large registry that collects information from people with Crohn's disease or Ulcerative Colitis who are using approved medications. It aims to understand how well these treatments work and how safe they are in real-world settings over time. The study does not test…

This study is creating a large, long-term registry of patients with Crohn's disease or ulcerative colitis to learn how these conditions behave and how treatments perform in everyday clinic settings. It will follow 15,000 adults and children (age 2+) for five years, collecting inf…

This study is building a collection of blood, stool, and urine samples, along with health information, from people with and without Inflammatory Bowel Disease (IBD). Researchers will use this 'biobank' to learn more about what causes IBD and how it progresses. The goal is to gath…

This study aims to see if computer programs can help doctors better assess inflammatory bowel disease (IBD). Researchers will analyze existing medical scans and videos from 200 patients to create new computer-generated measurements. The goal is to compare these computer readings …

This study aims to understand how the immune system works in people with inflammatory bowel disease (IBD), graft-versus-host disease (GVHD), and other related conditions. Researchers will collect blood and tissue samples from about 1,000 participants, including patients and healt…

This study aims to understand how genetics, lifestyle, and other factors influence the progression and severity of many common chronic diseases. Researchers will collect health records, genetic data, and samples from 120,000 participants with conditions like diabetes, arthritis, …

This study is testing a new tool—a thin probe inserted through the nose—to measure the health of the gut lining. Researchers want to see if this device can safely and accurately detect changes in 'gut permeability,' which is linked to conditions like Crohn's disease. The study in…