Stem cell shot for pouchitis fails to launch
NCT ID NCT05578508
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aimed to test whether injecting stem cells from a donor's bone marrow into the pouch (a surgically created internal reservoir) could safely treat pouchitis that hadn't improved with antibiotics or other drugs. The trial was planned for 12 adults aged 18-75 in the U.S., but it was withdrawn before any participants were enrolled, so no data were collected.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Allogeneic bone marrow derived mesenchymal stem cells (MSCs)
- What this could lead to
- If it had worked, this could point toward a new treatment option for people with pouchitis that doesn't respond to standard therapies.
- What could go wrong
- The trial was withdrawn before any patients were enrolled, so no results are available. Stem cell treatments are still experimental and may carry risks like infection or immune reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cleveland Clinic
Cleveland, Ohio, 44195, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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