POUCHITIS
Clinical trials for POUCHITIS explained in plain language.
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New hope for pouchitis sufferers: experimental drug enters trial
Disease control Recruiting nowThis study tests an experimental drug called CLF065 in 20 adults with chronic pouchitis, a condition causing inflammation in a surgically created internal pouch. Participants receive weekly doses of CLF065 or a placebo to see if the drug safely reduces symptoms and inflammation. …
Matched conditions: POUCHITIS
Phase: PHASE2 • Sponsor: Calibr, a division of Scripps Research • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New combo tackles stubborn gut inflammation after colitis surgery
Disease control Recruiting nowThis study tests whether the drug guselkumab (Tremfya), with or without a low-processed-food diet, can help people with chronic pouchitis—a painful gut condition that can occur after surgery for ulcerative colitis. Twenty adults who have not responded to antibiotics will receive …
Matched conditions: POUCHITIS
Phase: PHASE4 • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New drug trial aims to soothe painful pouchitis
Disease control Recruiting nowThis study tests whether mirikizumab (Omvoh) can reduce symptoms of chronic pouchitis, a condition where the internal pouch created after colon surgery becomes inflamed. Twenty-five adults will receive the drug every four weeks for a year. Researchers will track symptom changes u…
Matched conditions: POUCHITIS
Phase: PHASE4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New hope for kids with pouchitis: drug trial targets inflammation
Disease control Recruiting nowThis study tests whether vedolizumab (Entyvio) can improve symptoms and reduce inflammation in children with chronic pouchitis, a condition where an internal pouch becomes inflamed after bowel surgery. About 30 children will receive up to 12 infusions over 82 weeks. The main goal…
Matched conditions: POUCHITIS
Phase: PHASE3 • Sponsor: Takeda • Aim: Disease control
Last updated Jun 26, 2026 19:09 UTC
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New drug aims to stop pouchitis before it starts
Prevention Recruiting nowThis study tests whether the drug etrasimod can prevent pouchitis, a common inflammation of the internal pouch created after colon removal surgery. Researchers will give either etrasimod or a placebo to 40 high-risk patients for 48 weeks and track how many develop pouchitis. The …
Matched conditions: POUCHITIS
Phase: PHASE2 • Sponsor: Maia Kayal • Aim: Prevention
Last updated Jun 27, 2026 13:06 UTC