New drug trial aims to soothe painful pouchitis

NCT ID NCT06864403

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether mirikizumab (Omvoh) can reduce symptoms of chronic pouchitis, a condition where the internal pouch created after colon surgery becomes inflamed. Twenty-five adults will receive the drug every four weeks for a year. Researchers will track symptom changes using a standard scoring system.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mirikizumab (Omvoh)

What this could lead to

If it works, this could offer a new treatment option for people with chronic pouchitis, reducing symptoms and improving quality of life.

What could go wrong

This is a small, early-phase study with only 25 participants, so results may not apply to everyone. The drug may not work as hoped, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ileal neoplasm pouchitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Allegheny Health Network

    NOT_YET_RECRUITING

    Pittsburgh, Pennsylvania, 15212, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UCLA Vatche & Tamar Manoukian Division of Digestive Diseases

    RECRUITING

    Los Angeles, California, 90024, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of North Carolina

    RECRUITING

    Chapel Hill, North Carolina, 27599-7080, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••