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Frozen poop pills could tame ulcerative colitis

NCT ID NCT03843385

Ongoing Disease control Sponsor: Andreas Stallmach Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 11, 2026 · Updated 3 times

Summary

This study tests whether frozen capsules containing processed stool from healthy donors can help people with mild-to-moderate active ulcerative colitis. Participants will take either the real capsules or a placebo for 12 weeks. The goal is to see if the treatment can bring the disease into remission without the need for ongoing strong medications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
frozen stool capsules (fecal microbiota transplant or filtrate)
What this could lead to
If it works, this could offer a new, non-drug way to control ulcerative colitis and reduce symptoms without long-term medication.
What could go wrong
This is a phase 3 trial, but results are not yet known. The treatment may not work better than placebo, and some people may not respond or could have side effects like bloating or infection risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

inflammatory bowel disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLAMMATORY BOWEL DISEASES ULCERATIVE COLITIS

Contacts and locations

Locations

  • Agaplesion Markus Krankenhaus

    Frankfurt, Germany

  • Charité Berlin

    Berlin, Germany

  • DRK Kliniken Berlin Westend

    Berlin, Germany

  • FAU Universität Erlangen-Nürnberg

    Erlangen, Germany

  • Gesellschaft Klinische Studien Leipzig

    Leipzig, Germany

  • Havelhöhe

    Berlin, Germany

  • Jena University Hospital

    Jena, Thuringia, Germany

  • Klinikum Fulda

    Fulda, Germany

  • Krankenhaus Waldfriede

    Berlin, Germany

  • LMU Klinikum München - Campus Großhadern

    München, Germany

  • Otto-von-Guericke-Universität - Medizinische Fakultät

    Magdeburg, Germany

  • Sozialstiftung Bamberg

    Bamberg, Germany

  • St. Marien- und St. Annastiftskrankenhaus

    Ludwigshafen, Germany

  • Städtisches Klinikum Lüneburg

    Lüneburg, Germany

  • Universitätsklinik Freiburg

    Freiburg im Breisgau, Germany

  • Universitätsklinikum Carl Gustav Carus Dresden

    Dresden, Germany

  • Universitätsklinikum Halle (Saale)

    Halle, Germany

  • Universitätsklinikum Hamburg-Eppendorf

    Hamburg, Germany

  • Universitätsklinikum Schleswig Holstein

    Kiel, Germany

  • Universitätsklinikum Ulm

    Ulm, Germany

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