Frozen poop pills could tame ulcerative colitis

NCT ID NCT03843385

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether frozen capsules containing processed stool from healthy donors can help people with mild-to-moderate active ulcerative colitis. Participants will take either the real capsules or a placebo for 12 weeks. The goal is to see if the treatment can bring the disease into remission without the need for ongoing strong medications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

frozen stool capsules (fecal microbiota transplant or filtrate)

What this could lead to

If it works, this could offer a new, non-drug way to control ulcerative colitis and reduce symptoms without long-term medication.

What could go wrong

This is a phase 3 trial, but results are not yet known. The treatment may not work better than placebo, and some people may not respond or could have side effects like bloating or infection risk.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

inflammatory bowel disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Agaplesion Markus Krankenhaus

    RECRUITING

    Frankfurt, Germany

    Contact

  • Charité Berlin

    RECRUITING

    Berlin, Germany

    Contact

  • DRK Kliniken Berlin Westend

    RECRUITING

    Berlin, Germany

    Contact

  • FAU Universität Erlangen-Nürnberg

    RECRUITING

    Erlangen, Germany

    Contact

  • Gesellschaft Klinische Studien Leipzig

    RECRUITING

    Leipzig, Germany

    Contact

  • Havelhöhe

    RECRUITING

    Berlin, Germany

    Contact

  • Jena University Hospital

    RECRUITING

    Jena, Thuringia, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Klinikum Fulda

    RECRUITING

    Fulda, Germany

    Contact

  • Krankenhaus Waldfriede

    RECRUITING

    Berlin, Germany

    Contact

  • LMU Klinikum München - Campus Großhadern

    RECRUITING

    München, Germany

    Contact

  • Otto-von-Guericke-Universität - Medizinische Fakultät

    RECRUITING

    Magdeburg, Germany

    Contact

  • Sozialstiftung Bamberg

    RECRUITING

    Bamberg, Germany

    Contact

  • St. Marien- und St. Annastiftskrankenhaus

    RECRUITING

    Ludwigshafen, Germany

    Contact

  • Städtisches Klinikum Lüneburg

    RECRUITING

    Lüneburg, Germany

    Contact

  • Universitätsklinik Freiburg

    RECRUITING

    Freiburg im Breisgau, Germany

    Contact

  • Universitätsklinikum Carl Gustav Carus Dresden

    RECRUITING

    Dresden, Germany

    Contact

  • Universitätsklinikum Halle (Saale)

    RECRUITING

    Halle, Germany

    Contact

  • Universitätsklinikum Hamburg-Eppendorf

    RECRUITING

    Hamburg, Germany

    Contact

  • Universitätsklinikum Schleswig Holstein

    RECRUITING

    Kiel, Germany

    Contact

  • Universitätsklinikum Ulm

    RECRUITING

    Ulm, Germany

    Contact