120,000-Person study hopes to crack the code of chronic illness

NCT ID NCT04306939

Terminated Knowledge-focused Sponsor: University of Pittsburgh Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study plans to enroll 120,000 people with various chronic diseases like pancreatitis, diabetes, and arthritis. Researchers will collect blood samples and health data to study how genetics and lifestyle affect disease progression. The goal is to find common disease mechanisms and potential new uses for existing drugs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help identify new drug targets and ways to repurpose existing medications for multiple chronic diseases.
What could go wrong: This is an observational study, not a treatment trial. It is currently suspended, and results may take years to translate into actual therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE PANCREATITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute pancreatitis celiac disease cholecystitis cholelithiasis chronic diarrheal disease Chronic Disease chronic kidney disease Chronic Pain chronic pain syndrome chronic pancreatitis chronic renal failure syndrome congenital bile acid synthesis defect constipation disorder Crohn disease cystic fibrosis diabetes mellitus Dyslipidemias exocrine pancreatic insufficiency Fibrosis gastritis hepatitis hyperlipidemia inflammatory bowel disease inherited lipid metabolism disorder irritable bowel syndrome metabolic dysfunction-associated steatohepatitis metabolic dysfunction-associated steatotic liver disease multiple sclerosis Pancreatic Cyst pancreatic intraductal papillary-mucinous neoplasm pancreatitis primary biliary cholangitis rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE PANCREATITIS BILE ACID SYNTHESIS DEFECT BILIARY CIRRHOSIS CELIAC DISEASE CHOLECYSTITIS CHOLELITHIASES CHRONIC DISEASE CHRONIC KIDNEY DISEASES CHRONIC PAIN CHRONIC PANCREATITIS CONSTIPATION - FUNCTIONAL CONSTIPATION CHRONIC IDIOPATHIC CROHN DISEASE CYST PANCREAS CYSTIC FIBROSIS DIABETES MELLITUS DIARRHEA CHRONIC DYSLIPIDEMIAS GASTRITIS HEPATITIS INFLAMMATORY BOWEL DISEASES IPMN IRRITABLE BOWEL SYNDROME MULTIPLE SCLEROSIS NASH - NONALCOHOLIC STEATOHEPATITIS PANCREATIC EXOCRINE INSUFFICIENCY RHEUMATOID ARTHRITIS

Contacts and locations

Locations

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.