ACUTE PANCREATITIS

This study is testing if a single intravenous dose of a drug called infliximab can help adults hospitalized with sudden, severe pancreatitis. The drug aims to quickly reduce the dangerous body-wide inflammation caused by the condition. About 290 participants will be randomly assi…

This study is testing whether a new drug called CM4620 can safely reduce the severity of a serious pancreas inflammation (acute pancreatitis) that sometimes occurs in children and young adults receiving a specific chemotherapy drug (asparaginase) for leukemia. Researchers will gi…

This study is testing whether a single injection of an experimental drug called RABI-767 can help control severe acute pancreatitis. Doctors will give the injection directly near the pancreas using an ultrasound-guided endoscope. The trial will compare patients who receive this i…

This study is testing a new tool for a procedure to remove dead tissue from the pancreas, a serious complication of severe pancreatitis. Instead of using standard grabbers, doctors will use a special freezing probe that sticks to the dead tissue, aiming to remove it more complete…

This study is testing whether transplanting healthy gut bacteria from a donor (a fecal microbiota transplant or FMT) can help patients with moderate to severe acute pancreatitis. The goal is to see if this treatment can prevent dangerous late complications like pancreatic infecti…

This study aims to find the safest time to remove the gallbladder after a severe bout of pancreatitis caused by gallstones. Researchers will compare performing the surgery early during the initial hospital stay versus waiting about 4 weeks after the patient recovers. The main goa…

This study aims to understand how often dangerous blood clots form in the major abdominal veins of people hospitalized with sudden pancreatitis. Researchers will observe 500 patients to see if these clots are more common in severe cases and track what happens to the clots over si…

This study is creating a large collection of medical information and biological samples from people with various pancreatic conditions. Researchers will collect blood, saliva, leftover tissue, and survey data from up to 20,000 participants. The goal is to build a resource that he…

This study aims to understand why and how often diabetes develops after a person has acute pancreatitis. Researchers will follow 800 people for three years, performing regular blood sugar tests and health surveys. The goal is to learn the underlying causes and identify who is mos…

This study aims to find out if a continuous glucose monitor (CGM) can predict who will develop diabetes or pre-diabetes after having acute pancreatitis. Researchers will follow 800 people who recently had pancreatitis, using the monitor and other tests over three years to spot ea…

This study is creating a registry to track the results of a standard endoscopic procedure used to drain painful fluid collections that can form after pancreatitis. It will follow 1,000 adult patients who are already scheduled to receive this treatment as part of their normal care…