Could a simple phosphate IV ease severe pancreatitis?

NCT ID NCT07681050

Recruiting now Disease control Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 17, 2026 · Updated 5 times

Summary

This study investigates whether giving phosphate through an IV can reduce the severity of acute pancreatitis in adults. Researchers want to know if low phosphate levels make the disease worse and if replenishing it helps. Participants receive either standard care or IV phosphate during their hospital stay, with blood samples and follow-up assessments to track outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sodium Phosphate or Potassium Phosphate (given intravenously)
What this could lead to: If it works, this could point toward a simple, low-cost treatment to reduce the severity of acute pancreatitis.
What could go wrong: This is a small, early-phase study (100 people) at one hospital. It is designed mainly to test feasibility and dosing, not yet to prove effectiveness. The treatment may not improve outcomes.

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Conditions

The condition(s) this trial relates to.

acute pancreatitis hyperphosphatemia hypophosphatemia pancreatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATITIS

Contacts and locations

Locations

Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States

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