Common painkiller may prevent pancreatitis after bile duct procedure
NCT ID NCT07661498
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether a single dose of rectal indomethacin, a common anti-inflammatory drug, can prevent pancreatitis in patients undergoing a bile duct procedure (ERCP) who have had a prior sphincterotomy. About 860 adults will be randomly assigned to receive the drug or no drug before the procedure. The study aims to see if this simple preventive measure reduces the risk of post-procedure pancreatitis in this specific group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- indomethacin (rectal suppository)
- What this could lead to
- If effective, this could provide a simple, low-cost way to prevent pancreatitis after ERCP in patients who have had a prior sphincterotomy.
- What could go wrong
- This is a phase 4 trial in a specific, lower-risk population, so results may not apply broadly. The drug may not show significant benefit over no treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of California, San Francisco
San Francisco, California, 94158, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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