New drug aims to tame chemotherapy side effect in young cancer patients

NCT ID NCT04195347

Recruiting now Disease control Sponsor: St. Jude Children's Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called CM4620 in children and young adults who develop pancreatitis (inflammation of the pancreas) from a chemotherapy drug called asparaginase. The goal is to see if CM4620 is safe and can prevent severe complications like pancreatic cysts or tissue death. About 42 participants with leukemia or lymphoma will take CM4620 alongside their regular cancer treatment.

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Conditions

The condition(s) this trial relates to.

acute pancreatitis pancreatitis Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE PANCREATITIS

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Cincinnati Children's Hospital Medical Center
RECRUITING

Cincinnati, Ohio, 45220, United States
Novant Health Presbyterian Hemby Children's Hospital
RECRUITING

Charlotte, North Carolina, 28204, United States
St. Jude Children's Research Hospital
RECRUITING

Memphis, Tennessee, 38105, United States

Contact Email: •••••@•••••

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