ACUTE PANCREATITIS

This study looks at the best time to remove the gallbladder in people with severe pancreatitis caused by gallstones. Researchers will compare having surgery during the hospital stay versus waiting about a month after recovery. The goal is to see which approach leads to fewer majo…

This study tests whether transplanting healthy gut bacteria (FMT) can prevent serious infections in people with moderate to severe acute pancreatitis. About 80 adults will receive either FMT or a placebo. The goal is to see if FMT lowers the risk of infected pancreatic tissue, se…

This study tests a medicine called CM4620 in children and young adults who develop pancreas inflammation (pancreatitis) from a chemotherapy drug called asparaginase. The goal is to see if CM4620 is safe and can reduce the severity of the pancreatitis, including preventing serious…

This study tests a single dose of RABI-767, given via a thin tube into the belly, for people with predicted severe pancreatitis. About 36 adults will either get the drug plus standard care or standard care alone. The goal is to see if the drug is safe and helps prevent serious co…

This study is testing if a single dose of an existing anti-inflammatory drug, infliximab, can help control the severe inflammation caused by acute pancreatitis. Adults recently hospitalized with the condition will receive either a low dose, a high dose, or a placebo infusion. The…

This study tests whether fecal microbiota transplantation (FMT) can prevent serious infections in people with moderately severe or severe acute pancreatitis. About 150 adults aged 18-75 who are in the later phase of the disease will receive FMT or a placebo through a feeding tube…

This study tests a special freezing tool (cryoprobe) to remove dead tissue from the pancreas in people with a serious complication of pancreatitis. The standard method uses tools like forceps, but the dead tissue can be sticky and hard to grab. The cryoprobe freezes the tissue so…

This study follows 800 people who recently had acute pancreatitis to understand why some develop diabetes afterward. Participants will be monitored for 36 months with tests and surveys. No new treatments are tested—the goal is to learn more about the link between pancreatitis and…

This study is a registry that will collect information from up to 1,000 adults who receive standard endoscopic treatment for fluid collections caused by pancreatitis. The goal is to see how well the treatment works and what outcomes patients experience. No new treatments are bein…

This study follows 800 people who recently had acute pancreatitis to see if a continuous glucose monitor (CGM) can predict who will develop diabetes or pre-diabetes. Researchers will track participants for 36 months using CGM and other tests. The goal is to improve how doctors mo…

This study watches 500 adults with acute pancreatitis to see how often blood clots form in key belly veins (splenic, portal, or superior mesenteric). Researchers will check if these clots are linked to more severe pancreatitis and complications like infected fluid collections. No…

This study collects medical information, blood, tissue, and other samples from up to 20,000 people with pancreas diseases like pancreatic cancer or pancreatitis. The goal is to build a resource that helps researchers better understand these conditions and develop better screening…